Double-Network Hydrogel Armored Decellularized Porcine Pericardium as Durable Bioprosthetic Heart Valves.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202102059
Abstract: Heart valve has extraordinary fatigue resistance which beats ∼3 billion times in a lifetime. Bioprosthetic heart valves (BHVs) made from fixed heteroplasm that are incrementally used in heart valve replacement fail to sustain the expected… read more here.
Keywords: heart valves; heart; double network; bioprosthetic heart ... See more keywords
A novel anti-calcification method for bioprosthetic heart valves using dopamine-modified alginate
Sign Up to like & getrecommendations! Published in 2018 at "Polymer Bulletin"
DOI: 10.1007/s00289-018-2450-7
Abstract: Calcification is one of the main causes for bioprosthetic heart valves (BHVs)’ failure. Reported strategies to improve BHVs’ anti-calcification properties only target some of risk factors for calcification. In the current study, we demonstrated dopamine-modified… read more here.
Keywords: alginate; bioprosthetic heart; bhvs; calcification ... See more keywords
Bridging Anticoagulation with Mechanical Heart Valves: Current Guidelines and Clinical Decisions
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DOI: 10.1007/s11886-020-01390-2
Abstract: The management of patients with mechanical heart valves who require surgery or invasive procedures is a common clinical scenario in contemporary practice. The risk of thromboembolism versus the risk of bleeding is the foundation of… read more here.
Keywords: heart; bridging anticoagulation; anticoagulant therapy; mechanical heart ... See more keywords
Monocytes and Macrophages in Heart Valves: Uninvited Guests or Critical Performers?
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biomedical engineering"
DOI: 10.1016/j.cobme.2018.02.003
Abstract: Monocytes and macrophages are critical components of the myeloid niche of the innate immune system. In addition to traditional roles as phagocytes, this subsection of innate immunity has been implicated in its ability to regulate… read more here.
Keywords: monocytes macrophages; macrophages heart; uninvited guests; valves uninvited ... See more keywords
Maternal and Fetal Outcomes of Anticoagulation in Pregnant Women With Mechanical Heart Valves
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2017.03.605
Abstract: Background Anticoagulation for mechanical heart valves during pregnancy is essential to prevent thromboembolic events. Each regimen has drawbacks with regard to maternal or fetal risk. Objectives This meta-analysis sought to estimate and compare the risk… read more here.
Keywords: risk; vka; mechanical heart; maternal fetal ... See more keywords
Low-Thrombogenicity Mechanical Heart Valves: Which Antithrombotic Strategy?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.07.065
Abstract: We read with interest the results of the PROACT (Prospective Randomized On-X Anticoagulation Trial) trial [(1)][1], which evaluated possible alternatives to standard warfarin therapy for carriers of a low-thrombogenicity mechanical heart valve (MHV). We comment… read more here.
Keywords: mechanical heart; low thrombogenicity; thrombogenicity mechanical; heart valves ... See more keywords
Tomographic PIV in a model of the left ventricle: 3D flow past biological and mechanical heart valves.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2019.04.024
Abstract: Left ventricular flow is intrinsically complex, three-dimensional and unsteady. Its features are susceptible to cardiovascular pathology and treatment, in particular to surgical interventions involving the valves (mitral valve replacement). To improve our understanding of intraventricular… read more here.
Keywords: left ventricle; mechanical heart; flow; heart valves ... See more keywords
3D PRINTED HEART VALVES: CHALLENGES AND OPPORTUNITIES
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American College of Cardiology"
DOI: 10.1016/s0735-1097(20)34168-1
Abstract: 3D printing holds the promise of constructing precision replacement heart valves with patient-specific customization and optimization. Can functional heart valves be 3D printed? Five heart valves were designed in CAD and fabricated using a Polyjet… read more here.
Keywords: challenges opportunities; heart; valves challenges; cardiology ... See more keywords
Future prospects in the tissue engineering of heart valves: a focus on the role of stem cells.
Sign Up to like & getrecommendations! Published in 2023 at "Expert opinion on biological therapy"
DOI: 10.1080/14712598.2023.2214313
Abstract: INTRODUCTION Heart valve disease is a growing burden on the healthcare system. Current solutions are insufficient for young patients and do not offer relief from reintervention. Tissue engineered heart valves (TEHVs) offer a solution that… read more here.
Keywords: tissue engineering; cell populations; heart; stem cells ... See more keywords
Off-the-shelf tissue engineered heart valves for in situ regeneration: current state, challenges and future directions
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Medical Devices"
DOI: 10.1080/17434440.2018.1419865
Abstract: ABSTRACT Introduction: Transcatheter aortic valve replacement (TAVR) is continuously evolving and is expected to surpass surgical valve implantation in the near future. Combining durable valve substitutes with minimally invasive implantation techniques might increase the clinical… read more here.
Keywords: engineered heart; tissue; tissue engineered; valve ... See more keywords
Management of therapeutic anticoagulation in patients with intracerebral haemorrhage and mechanical heart valves
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DOI: 10.1093/eurheartj/ehy056
Abstract: Aims Evidence is lacking regarding acute anticoagulation management in patients after intracerebral haemorrhage (ICH) with implanted mechanical heart valves (MHVs). Our objective was to investigate anticoagulation reversal and resumption strategies by evaluating incidences of haemorrhagic… read more here.
Keywords: anticoagulation; heart; intracerebral haemorrhage; mechanical heart ... See more keywords