Articles with "heavily mutated" as a keyword



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Omicron: A Heavily Mutated SARS-CoV-2 Variant Exhibits Stronger Binding to ACE2 and Potently Escapes Approved COVID-19 Therapeutic Antibodies

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Published in 2021 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2021.830527

Abstract: The new SARS-CoV-2 variant of concern “Omicron” was recently spotted in South Africa and spread quickly around the world due to its enhanced transmissibility. The variant became conspicuous as it harbors more than 30 mutations… read more here.

Keywords: omicron heavily; sars cov; heavily mutated; therapeutic antibodies ... See more keywords
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Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2

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Published in 2022 at "Vaccines"

DOI: 10.3390/vaccines10081172

Abstract: The Omicron SARS-CoV-2 variant has been designated as a variant of concern because its spike protein is heavily mutated. In particular, the Omicron spike is mutated at five positions (K417, N440, E484, Q493, and N501)… read more here.

Keywords: heavily mutated; fully protected; mouse adapted; strain sars ... See more keywords