Oral or intravenous vinorelbine plus capecitabine in heavily pretreated HER2 negative metastatic breast cancer; similar effect or quality of life?
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05220-0
Abstract: I want to congratulate Torres and their colleagues [1] in which they investigated evaluated the efficacy and safety of the Vinorelbine/Capecitabine doublet (VINOCAP) in heavily pretreated HER2 negative metastatic breast cancer (MBC) patients with vinorelbine… read more here.
Keywords: vinorelbine; heavily pretreated; breast cancer; her2 negative ... See more keywords
Restoring Immune Mediated Disease Control by Ipilimumab Re-exposition in a Heavily pretreated Patient With MSI-H mCRC.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical colorectal cancer"
DOI: 10.1016/j.clcc.2022.01.003
Abstract: BACKGROUND Immune-Checkpoint-inhibitors (ICIs) are approved in first line therapy of microsatellite-instable, deficient miss-match-repair (MSI-H-dMMR) metastatic colorectal cancer (mCRC), and in second line after standard chemotherapy. Evidence supporting immunotherapy after immunotherapy is scarce. CASE REPORT This… read more here.
Keywords: disease control; mediated disease; disease; heavily pretreated ... See more keywords
Cost-effectiveness of Pomalidomide, Carfilzomib, and Daratumumab for the Treatment of Patients with Heavily Pretreated Relapsed-refractory Multiple Myeloma in the United States.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2017.08.010
Abstract: PURPOSE Pomalidomide plus low-dose dexamethasone (POM-d), daratumumab monotherapy (DARA), and carfilzomib monotherapy (CAR) have been approved for use in the treatment of patients with heavily pretreated relapsed-refractory multiple myeloma (RRMM) in the US, based on… read more here.
Keywords: life years; treatment; heavily pretreated; cost ... See more keywords
A phase II study of Navitoclax (ABT-263) as single agent in women heavily pretreated for recurrent epithelial ovarian cancer: The MONAVI - GINECO study.
Sign Up to like & getrecommendations! Published in 2022 at "Gynecologic oncology"
DOI: 10.1016/j.ygyno.2022.01.021
Abstract: BACKGROUND There are limited treatment options for ovarian cancer patients with early relapse after platinum chemotherapy. In preclinical studies, we previously demonstrated the promising activity of ABT-737, a Bcl-2/Bcl-xL anti-apoptotic protein inhibitor, in chemo-resistant ovarian… read more here.
Keywords: study; heavily pretreated; phase study; ovarian cancer ... See more keywords
Programmed cell death protein 1 (PD-1)-inhibition in hepatocellular carcinoma (HCC): a single center experience
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2020.1794539
Abstract: Abstract Background The prognosis for advanced Hepatocellular carcinoma (HCC)is still very poor. Despite initial usefulness of immune checkpoint inhibitor (PD-1), phase 3 trials failed to show significant benefit of PD-1 inhibition with nivolumab or pembrolizumab… read more here.
Keywords: hepatocellular carcinoma; hcc; carcinoma hcc; inhibition ... See more keywords
Stereotactic body radiation therapy and thymosin alpha-1-induced anti-tumor effects in heavily pretreated, metastatic esophageal squamous cell carcinoma patients
Sign Up to like & getrecommendations! Published in 2018 at "OncoImmunology"
DOI: 10.1080/2162402x.2018.1450128
Abstract: ABSTRACT This study investigated the anti-tumor effects of stereotactic body radiation therapy (SBRT) with thymosin alpha-1 (Tα1) in heavily pretreated, metastatic esophageal squamous cell carcinoma (mESCC) patients. Thirty-one patients with at least 2 metastatic sites… read more here.
Keywords: tumor; heavily pretreated; tumor effects; anti tumor ... See more keywords
P17.07.A Metronomic temozolomide therapy in heavily pretreated patients with recurrent glioblastoma: a large mono-institutional retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noac174.315
Abstract: Glioblastoma (GBM) is the most common and aggressive primary brain cancer. Despite advances in surgical and first-line treatment, all pts relapse. The aim of this study is to evaluate the benefit of metronomic Temozolomide (mTMZ)… read more here.
Keywords: oncology; metronomic temozolomide; heavily pretreated; therapy ... See more keywords
Pronounced clinical response following the oncolytic vaccinia virus GL-ONC1 and chemotherapy in a heavily pretreated ovarian cancer patient.
Sign Up to like & getrecommendations! Published in 2019 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000000836
Abstract: Heavily pretreated ovarian cancer patients become progressively chemoresistant, and thereafter, only scant treatments potentially accord reasonable, albeit limited clinical efficacy. We describe a case involving a 67-year-old ovarian cancer patient who underwent multiple lines of… read more here.
Keywords: ovarian cancer; pretreated ovarian; heavily pretreated; cancer ... See more keywords
A pilot study of oral S-1 for treating heavily pretreated patients with advanced or recurrent cervical cancer among Chinese population
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000010922
Abstract: Abstract This pilot study retrospectively aimed to assess the feasibility effectiveness and safety of oral S-1 in heavily pretreated patients with advanced or recurrent cervical cancer (ARCC) among Chinese population. Thirty patients with ARCC who… read more here.
Keywords: pilot study; pretreated patients; heavily pretreated; among chinese ... See more keywords
Allogeneic Hematopoietic Stem Cell Transplantation For Heavily Pretreated Patients With Mycosis Fungoides and Sezary Syndrome.
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic therapy"
DOI: 10.1111/dth.15447
Abstract: Allogeneic hematopoietic stem cell transplantation (AHSCT) is a promising strategy for treatment of heavily pretreated mycosis fungoides/Sezary syndrome (MF/SS). Herein, we aimed to evaluate the outcomes of AHSCT for heavily pretreated patients with MF/SS retrospectively.… read more here.
Keywords: allogeneic hematopoietic; pretreated patients; heavily pretreated; cell ... See more keywords
Ibrutinib and antimicrobial therapy in a heavily pretreated patient with chronic lymphocytic leukaemia and disseminated cutaneous non‐tuberculous mycobacterial infection: successful surgery‐free approach
Sign Up to like & getrecommendations! Published in 2018 at "Internal Medicine Journal"
DOI: 10.1111/imj.13756
Abstract: 1 Leonardi-Bee J, Pritchard D, Britton J. Asthma and current intestinal parasite infection: systematic review and metaanalysis. Am J Respir Crit Care Med 2006; 174: 514–23. 2 KhanAR, Fallon PG.Helminth therapies: translating the unknownunknowns to… read more here.
Keywords: ibrutinib antimicrobial; infection; antimicrobial therapy; heavily pretreated ... See more keywords