Articles with "hect" as a keyword



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A HECT domain ubiquitin ligase CgWWP1 regulates granulocytes proliferation in oyster Crassostrea gigas.

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Published in 2021 at "Developmental and comparative immunology"

DOI: 10.1016/j.dci.2021.104148

Abstract: Ubiquitination is involved in the regulation of granulocyte proliferation in vertebrate, and E3 ubiquitin ligase WWP1 has been reported to play an essential role in this process. In the present study, an HECT type E3… read more here.

Keywords: ubiquitin ligase; proliferation; hect; cgwwp1 ... See more keywords
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A Tunable Brake for HECT Ubiquitin Ligases.

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Published in 2017 at "Molecular cell"

DOI: 10.1016/j.molcel.2017.03.020

Abstract: The HECT E3 ligases ubiquitinate numerous transcription factors and signaling molecules, and their activity must be tightly controlled to prevent cancer, immune disorders, and other diseases. In this study, we have found unexpectedly that peptide… read more here.

Keywords: hect ubiquitin; tunable brake; ubiquitin ligases; hect ... See more keywords