The protective effects of thymol and carvacrol against di (2‐ethylhexyl) phthalate‐induced cytotoxicity in HEK‐293 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23092
Abstract: The protective effects of thymol and carvacrol, two phenolic monoterpenes with a wide spectrum of pharmacological effects, against the oxidative stress produced by the di (2‐ethylhexyl) phthalate (DEHP) in human embryonic kidney cells 293 cells… read more here.
Keywords: protective effects; 293 cells; thymol carvacrol; hek 293 ... See more keywords
Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2451-6
Abstract: PurposeThe aim of this study was to analyze the genetic and functional role of a novel RYR1 variant c.251 C > T (p.Thr84Met) identified in a patient with muscle weakness demonstrating MH susceptibility.MethodsDNA testing of family members… read more here.
Keywords: susceptibility; 293 cells; genetic functional; ryr1 ... See more keywords
Olive compounds attenuate oxidative damage induced in HEK-293 cells via MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.10.008
Abstract: Abstract The protective effects of ethanolic olive fruit extract (OFE) and purified oleuropein (Ole) have been evaluated against H2O2-induced oxidative damage and apoptosis in human embryonic kidney (HEK-293) cells. Olive compounds demonstrated a protective effect… read more here.
Keywords: 293 cells; oxidative damage; olive compounds; signaling pathway ... See more keywords
SA/G hydrogel containing NRF2-engineered HEK-293-derived CM improves wound healing efficacy of WJ-MSCs in a rat model of excision injury.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of tissue viability"
DOI: 10.1016/j.jtv.2021.07.009
Abstract: AIM OF THE STUDY Skin wounds are a major public health issue due to the lack of real effective remedies. Mesenchymal stem cells (MSCs) are considered as a promising therapeutic strategy for wound injuries; however,… read more here.
Keywords: wound healing; hydrogel; hydrogel containing; containing nrf2 ... See more keywords
Purification and characterization of a bioactive alpha-fetoprotein produced by HEK-293 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Protein expression and purification"
DOI: 10.1016/j.pep.2017.05.008
Abstract: Alpha-fetoprotein (AFP) is a biomarker that is used to diagnose hepatocellular carcinoma (HCC) and can promote malignancy in HCC. AFP is an important target in the treatment of liver cancer. To obtain enough AFP to… read more here.
Keywords: afp; 293 cells; hek 293; alpha fetoprotein ... See more keywords
Antioxidant, α-Glucosidases and α-Amylase Inhibitory Activities of Persicaria odorata
Sign Up to like & getrecommendations! Published in 2021 at "Chiang Mai University Journal of Natural Sciences"
DOI: 10.12982/cmujns.2021.051
Abstract: The objects of this study were to determine the effects to reactive oxygen species and antioxidant enzymes levels in HEK-293 cells and inhibition of α-glucosidases and α-amylase enzymes of extracts from Persicaria odorata or phak… read more here.
Keywords: persicaria odorata; amylase inhibitory; phak phaeo; antioxidant glucosidases ... See more keywords
Effects of equol on multiple K+ channels stably expressed in HEK 293 cells
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183708
Abstract: The present study investigated the effects of equol on cardiovascular K+ channel currents. The cardiovascular K+ channel currents were determined in HEK 293 cells stably expressing cloned differential cardiovascular K+ channels with conventional whole-cell patch… read more here.
Keywords: multiple channels; 293 cells; equol multiple; effects equol ... See more keywords
Thapsigargin blocks electromagnetic field‐elicited intracellular Ca2+ increase in HEK 293 cells
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15189
Abstract: Biological effects of electromagnetic fields (EMFs) have previously been identified for cellular proliferation and changes in expression and conduction of diverse types of ion channels. The major effect elicited by EMFs seems to be directed… read more here.
Keywords: thapsigargin blocks; increase; 293 cells; intracellular ca2 ... See more keywords
Effect of trans-sodium crocetinate on contrast-induced cytotoxicity in HEK-293 cells
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.64671.14234
Abstract: Objective(s): Contrast media (CM) are used for diagnostic or therapeutic intervention purposes in medicine. The main adverse reaction after the administration of CM is contrast-induced nephropathy (CIN). This complication is the third cause of renal… read more here.
Keywords: induced cytotoxicity; 293 cells; hek 293; contrast induced ... See more keywords
Enhanced Levels of Peroxisome-Derived H2O2 Do Not Induce Pexophagy but Impair Autophagic Flux in HEK-293 and HeLa Cells
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12030613
Abstract: Peroxisomes are functionally specialized organelles that harbor multiple hydrogen peroxide (H2O2)-producing and -degrading enzymes. Given that this oxidant functions as a major redox signaling agent, peroxisomes have the intrinsic ability to mediate and modulate H2O2-driven… read more here.
Keywords: autophagic flux; h2o2; impair autophagic; hek 293 ... See more keywords
Trio-Drug Combination of Sodium Valproate, Baclofen and Thymoquinone Exhibits Synergistic Anticonvulsant Effects in Rats and Neuro-Protective Effects in HEK-293 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb44100299
Abstract: Epilepsy is a chronic brain disorder, with anti-epileptic drugs (AEDs) providing relief from hyper-excitability of neurons, but largely failing to restrain neurodegeneration. We investigated a progressive preclinical trial in rats, whereby the test drugs; sodium… read more here.
Keywords: sodium valproate; trio drug; combination; drug combination ... See more keywords