A cancer/testis antigen, NY-SAR-35, induces EpCAM, CD44, and CD133, and activates ERK in HEK293 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.01.105
Abstract: The cancer/testis (CT) antigen NY-SAR-35 gene is located on the X chromosome and is aberrantly expressed in various cancers but not in normal tissues, other than testes. Previously, we reported the expression of NY-SAR-35 enhanced… read more here.
Keywords: hek293; hek293 cells; cancer testis; sar ... See more keywords
Exploring Site-Specific N-Glycosylation of HEK293 and Plant-Produced Human IgA Isotypes
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Proteome Research"
DOI: 10.1021/acs.jproteome.7b00121
Abstract: The full potential of recombinant Immunoglobulin A as therapeutic antibody is not fully explored, owing to the fact that structure–function relationships of these extensively glycosylated proteins are not well understood. Here monomeric IgA1, IgA2m(1), and… read more here.
Keywords: plant; site specific; hek293; plant produced ... See more keywords
Data for: Enabling HEK293 cells for antibiotic-free media bioprocessing through CRISPR/Cas9 gene editing
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.17632/wzgcvw42hn.1
Abstract: Abstract Unlike other cell lines used in industry, HEK293 have not well-established metabolic markers yet for the selection of positive transfected cells expressing recombinant proteins. Three different metabolic markers were explored and assessed in HEK293… read more here.
Keywords: crispr cas9; hek293; selection; gene ... See more keywords
Transport of Bupropion and its Metabolites by the Model CHO and HEK293 Cell Lines.
Sign Up to like & getrecommendations! Published in 2019 at "Drug metabolism letters"
DOI: 10.2174/1872312813666181129101507
Abstract: BACKGROUND Bupropion (BUP) is widely used as an antidepressant and smoking cessation aid. There are three major pharmacologically active metabolites of BUP, Erythrohydrobupropion (EB), Hydroxybupropion (OHB) and Threohydrobupropion (TB). At present, the mechanisms underlying the… read more here.
Keywords: bup; hek293 cell; cell lines; hek293 ... See more keywords
Improvement of HEK293 Cell Growth by Adapting Hydrodynamic Stress and Predicting Cell Aggregate Size Distribution
Sign Up to like & getrecommendations! Published in 2023 at "Bioengineering"
DOI: 10.3390/bioengineering10040478
Abstract: HEK293 is a widely used cell line in the fields of research and industry. It is assumed that these cells are sensitive to hydrodynamic stress. The aim of this research was to use particle image… read more here.
Keywords: cell; hek293; size distribution; hydrodynamic stress ... See more keywords
Patulin Alters Insulin Signaling and Metabolic Flexibility in HepG2 and HEK293 Cells
Sign Up to like & getrecommendations! Published in 2023 at "Toxins"
DOI: 10.3390/toxins15040244
Abstract: Non-communicable diseases (NCDs) have risen rapidly worldwide, sparking interest in causative agents and pathways. Patulin (PAT), a xenobiotic found in fruit products contaminated by molds, is postulated to be diabetogenic in animals, but little is… read more here.
Keywords: signaling pathway; hek293; patulin alters; hepg2 ... See more keywords