Glutamine synthetase gene knockout-human embryonic kidney 293E cells for stable production of monoclonal antibodies.
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DOI: 10.1002/bit.26552
Abstract: Previously, it was inferred that a high glutamine synthetase (GS) activity in human embryonic kidney (HEK) 293E cells results in elevated resistance to methionine sulfoximine (MSX) and consequently hampers GS-mediated gene amplification and selection by… read more here.
Keywords: glutamine synthetase; 293e cells; embryonic kidney; hek293e ... See more keywords