Fabrication of tumor-targeting composites based on the triple helical β-glucan through conjugation of aptamer.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.117476
Abstract: Herein the nucleic acid aptamers were attached to the polydeoxyadenylic acid (poly(dA)) tail for improving the tumor-targetability and cellular internalization of s-LNT/poly(dA) composite composed of two single chains of triple helical β-glucan lentinan (s-LNT) and… read more here.
Keywords: helical glucan; lnt; poly; triple helical ... See more keywords
The recognition mechanism of triple-helical β-1,3-glucan by a β-1,3-glucanase.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc03330c
Abstract: β-1,3-Glucan is one of the most abundant polysaccharides in fungi. Recognition of β-1,3-glucan occurs in both hydrolysis by glycoside hydrolases and immunological recognition. Our study provides a novel structural account of how glycoside hydrolase recognizes… read more here.
Keywords: helical glucan; recognition mechanism; recognition; glucan glucanase ... See more keywords