RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination
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DOI: 10.1016/j.molcel.2018.04.001
Abstract: Summary Class switch recombination (CSR) at the immunoglobulin heavy-chain (IgH) locus is associated with the formation of R-loop structures over switch (S) regions. While these often occur co-transcriptionally between nascent RNA and template DNA, we… read more here.
Keywords: helicase ddx1; rna helicase; switch; class switch ... See more keywords