CHD4 acts as a critical regulator in the survival of spermatogonial stem cells in mice
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac162
Abstract: Abstract Spermatogenesis is sustained by homeostatic balance between the self-renewal and differentiation of spermatogonial stem cells, which is dependent on the strict regulation of transcription factor and chromatin modulator gene expression. Chromodomain helicase DNA-binding protein… read more here.
Keywords: chromodomain helicase; spermatogonial stem; helicase dna; dna binding ... See more keywords
The role of chromodomain helicase DNA binding protein 1 (CHD1) in promoting an invasive prostate cancer phenotype
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Urology"
DOI: 10.1177/17562872211022462
Abstract: Background: Prostate cancer (PCa) phenotypes vary from indolent to aggressive. Molecular subtyping may be useful in predicting aggressive cancers and directing therapy. One such subtype involving deletions of chromodomain helicase DNA binding protein 1 (CHD1),… read more here.
Keywords: prostate; helicase dna; chd1; prostate cancer ... See more keywords
Genetic Variability of the Functional Domains of Chromodomains Helicase DNA-Binding (CHD) Proteins
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DOI: 10.3390/genes12111827
Abstract: In the past few years, there has been an increasing neuroscientific interest in understanding the function of mammalian chromodomains helicase DNA-binding (CHD) proteins due to their association with severe developmental syndromes. Mammalian CHDs include nine… read more here.
Keywords: chd proteins; helicase dna; chromodomains helicase; binding chd ... See more keywords