Synthetic Self-adjuvanted Lipopeptide Vaccines Conferred Protection Against Helicobacter pylori Infection.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300085
Abstract: Helicobacter pylori colonize the stomach epithelium of half the world's population and are responsible for various digestive diseases and even stomach cancer. Vaccine-mediated protection against Helicobacter pylori infection depends primarily on the specific mucosal and… read more here.
Keywords: protection helicobacter; pylori infection; helicobacter pylori; helicobacter ... See more keywords
An exploratory study on the presence of Helicobacter heilmannii and Helicobacter billis in the feces of companion dogs
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.765
Abstract: Abstract Background Companion animals like dogs play an important role in the lives of many people and are often considered to be members of families, but definitely, any contact with them poses an inherent risk… read more here.
Keywords: companion dogs; presence; heilmannii; helicobacter ... See more keywords
Cloning of Helicobacter suis cholesterol α-glucosyltransferase and production of an antibody capable of detecting it in formalin-fixed, paraffin-embedded gastric tissue sections
Sign Up to like & getrecommendations! Published in 2017 at "Histochemistry and Cell Biology"
DOI: 10.1007/s00418-017-1582-4
Abstract: Helicobacter suis (H. suis), formerly called Helicobacter heilmannii type 1 (H. heilmannii), is a gram-negative bacterium of the Helicobacter species. This pathogen infects the stomach of humans and animals such as dogs, cats, pigs, and… read more here.
Keywords: fixed paraffin; paraffin embedded; antibody; helicobacter ... See more keywords
Otitis media with effusion: The role of Helicobacter Pylori in its pathogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Medicine and Surgery"
DOI: 10.1016/j.amsu.2021.01.056
Abstract: Background Otitis Media with Effusion (OME) is the most common disease of the middle ear. Different factors play a role in its pathogenesis, such as viral and bacterial infections, allergy, morphological and functional changes of… read more here.
Keywords: otitis media; helicobacter; media effusion; role ... See more keywords
Co-expression of Interleukin-17A molecular adjuvant and prophylactic Helicobacter pylori genetic vaccine could cause sterile immunity in Treg suppressed mice.
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2019.154866
Abstract: The increasing clinical significance of Helicobacter pylori (H. pylori) in human stomach cancer has led to global efforts to eradicate this pathogen. Recent studies have confirmed the importance of some cytokines such as Interleukin-18 (IL-18),… read more here.
Keywords: immunity; interleukin 17a; helicobacter; helicobacter pylori ... See more keywords
Cryo-EM Analysis Reveals Structural Basis of Helicobacter pylori VacA Toxin Oligomerization.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2019.03.029
Abstract: Helicobacter pylori colonizes the human stomach and contributes to the development of gastric cancer and peptic ulcer disease. H. pylori secretes a pore-forming toxin called vacuolating cytotoxin A (VacA), which contains two domains (p33 and… read more here.
Keywords: vaca; helicobacter; toxin; oligomerization ... See more keywords
Whole genome-based phylogeny of reptile-associated Helicobacter indicates independent niche adaptation followed by diversification in a poikilothermic host
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-09091-7
Abstract: Reptiles have been shown to host a significant Helicobacter diversity. In order to survive, reptile-associated Helicobacter lineages need to be adapted to the thermally dynamic environment encountered in a poikilothermic host. The whole genomes of… read more here.
Keywords: associated helicobacter; helicobacter; host; adaptation ... See more keywords
Non-Helicobacter pylori Helicobacter (NHPH) positive gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-08962-y
Abstract: Genetic analysis and culturing techniques for gastric non-Helicobacter pylori Helicobacter (NHPH) are progressing. NHPH is reported to accompany nodular gastritis, gastric MALT lymphoma, and mild gastritis. However, only a few gastric cancer cases infected by… read more here.
Keywords: cancer; patient; nhph positive; non helicobacter ... See more keywords
Chemoenzymatic synthesis of an α-1,6-glucan-based conjugate vaccine against helicobacter pylori.
Sign Up to like & getrecommendations! Published in 2022 at "Glycobiology"
DOI: 10.1093/glycob/cwac023
Abstract: In this study, we investigated the utility of glycoconjugates based on a linear α-1,6-glucan chain synthesized using a recombinant α-1,6-glucosyltransferase from the 26,695 strain of Helicobacter pylori. Capillary electrophoresis-mass spectrometry (CE-MS) analysis confirmed the main… read more here.
Keywords: glucan based; synthesis glucan; helicobacter pylori; chemoenzymatic synthesis ... See more keywords
Helicobacter urease suppresses cytotoxic CD8 + T cell responses through activating Myh9-dependent induction of PD-L1.
Sign Up to like & getrecommendations! Published in 2021 at "International immunology"
DOI: 10.1093/intimm/dxab044
Abstract: As a key virulence factor for persistent colonization, Urease B subunit (UreB) is considered to be an ideal vaccine antigen against Helicobacter pylori (H. pylori) infection. However, the role and molecular mechanisms of UreB involved… read more here.
Keywords: cd8 cell; cell responses; cd8; cytotoxic cd8 ... See more keywords
IFNγ-dependent silencing of TFF1 during Helicobacter pylori infection
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220278
Abstract: Chronic Helicobacter pylori infection is the leading cause of intestinal-type adenocarcinoma, as prolonged Helicobacter colonization triggers chronic active gastritis, which may evolve into adenocarcinoma of the intestinal type. In this environment, cytokines play a significant… read more here.
Keywords: ifn dependent; pylori infection; infection; helicobacter ... See more keywords