Down-regulation of Helios Expression in Tregs from Patients with Hypertension
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DOI: 10.1007/s11596-018-1846-9
Abstract: Regulatory T cells (Tregs) play a pivotal role in the pathological development of hypertension. Helios, a transcription factor from the Ikaros family, was recently reported to be a bona fide marker for natural Tregs or… read more here.
Keywords: helios tregs; foxp3 helios; hypertension; role hypertension ... See more keywords
Soluble glucocorticoid-induced tumor necrosis factor receptor regulates Helios expression in myasthenia gravis
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DOI: 10.1186/s12967-019-1916-1
Abstract: BackgroundHelios is important for functional and phenotype stability of regulatory T cells (Tregs). However, the role of Helios in autoimmune diseases and its regulation remains unclear. This study aimed to investigate the role of Helios+… read more here.
Keywords: helios tregs; glucocorticoid induced; gitr; expression ... See more keywords
Correlations between Circulating and Tumor-Infiltrating CD4+ T Cell Subsets with Immune Checkpoints in Colorectal Cancer
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DOI: 10.3390/vaccines10040538
Abstract: T regulatory cells (Tregs) play different roles in the regulation of anti-tumor immunity in colorectal cancer (CRC), depending on the presence of different Treg subsets. We investigated correlations between different CD4+ Treg/T cell subsets in… read more here.
Keywords: immune checkpoints; foxp3 helios; cancer; cell subsets ... See more keywords