The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.07.028
Abstract: Helitrons are widespread eukaryotic DNA transposons that have significantly contributed to genome variability and evolution, in part because of their distinctive, replicative rolling-circle mechanism, which often mobilizes adjacent genes. Although most eukaryotic transposases form oligomers… read more here.
Keywords: dna; end; transposase; helitron ... See more keywords
Diversification of the Caenorhabditis heat shock response by Helitron transposable elements
Sign Up to like & getrecommendations! Published in 2019 at "eLife"
DOI: 10.7554/elife.51139
Abstract: Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular… read more here.
Keywords: heat shock; heat; caenorhabditis; helitron ... See more keywords