The E-helix is a central core in a conserved helical bundle involved in nucleotide binding and transmembrane domain intercalation in the ABC transporter superfamily.
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DOI: 10.1016/j.ijbiomac.2019.01.030
Abstract: ABC transporter proteins are involved in active transport, both in prokaryotes and eukaryotes. Sequence analysis of nucleotide binding domains (NBDs) of ABC proteins from all taxa revealed a well-conserved new motif having the signature: xT/ShxE/DNhxF,… read more here.
Keywords: nucleotide binding; abc transporter; domain; helix central ... See more keywords