Cotranslational Folding of a Pentarepeat β-Helix Protein.
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DOI: 10.1016/j.jmb.2018.10.016
Abstract: It is becoming increasingly clear that many proteins start to fold cotranslationally before the entire polypeptide chain has been synthesized on the ribosome. One class of proteins that a priori would seem particularly prone to… read more here.
Keywords: pentarepeat; folding; cotranslational folding; helix protein ... See more keywords
Mutations found in cancer patients compromise DNA binding of the winged helix protein STK19
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DOI: 10.1038/s41598-024-64840-9
Abstract: Serine/threonine protein kinase 19 (STK19) has been reported to phosphorylate and activate oncogenic NRAS to promote melanomagenesis. However, concerns have been raised about whether STK19 is a kinase. STK19 has also been identified as a… read more here.
Keywords: stk19; helix protein; helix; dna binding ... See more keywords