LAUSR

The Helix Twist: Damage and Repair Follows the DNA Minor Groove

Sign Up to like & get
recommendations!
1 Published in 2018 at "Cell"

DOI: 10.1016/j.cell.2018.10.034

Abstract: Mutation frequencies vary along the genome, but the factors determining this variability are only partially understood. Pich et al. unravel a ∼10 bp periodicity in mutation rates at nucleosome-proximal regions that follows minor groove orientation. Opposing differential… read more here.

Keywords: minor groove; helix twist; damage repair;