Unique glycan and lipid composition of helminth-derived extracellular vesicles may reveal novel roles in host-parasite interactions.
Sign Up to like & getrecommendations! Published in 2020 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2020.03.012
Abstract: Although the study of helminth-derived extracellular vesicles (EVs) is in its infancy, proteomic studies of EVs from representatives of nematodes, cestodes and trematodes have identified homologs of mammalian EV proteins including components of the endosomal… read more here.
Keywords: extracellular vesicles; helminth derived; host parasite; derived extracellular ... See more keywords
The helminth derived peptide FhHDM-1 redirects macrophage metabolism towards glutaminolysis to regulate the pro-inflammatory response
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1018076
Abstract: We have previously identified an immune modulating peptide, termed FhHDM-1, within the secretions of the liver fluke, Fasciola hepatica, which is sufficiently potent to prevent the progression of type 1 diabetes and multiple sclerosis in… read more here.
Keywords: metabolism; derived peptide; helminth derived; macrophage metabolism ... See more keywords