Regulatory T and T helper 17 cells: Their roles in preeclampsia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26604
Abstract: Regulatory T (Treg) cells have been identified as key immune regulators and are important to fetal survival within the maternal uterus. T helper 17 (Th17) cells have also emerged as a new subset of effector… read more here.
Keywords: treg cells; regulatory helper; th17 cells; helper cells ... See more keywords
Identification of two distinct populations of WT1-specific cytotoxic T lymphocytes in co-vaccination of WT1 killer and helper peptides
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02675-9
Abstract: Simultaneous induction of tumor antigen-specific cytotoxic T lymphocytes (CTLs) and helper T lymphocytes (HTLs) is required for an optimal anti-tumor immune response. WT1 332 , a 16-mer WT1-derived helper peptide, induce HTLs in an HLA… read more here.
Keywords: peptide; wt1 specific; wt1 ctl; wt1 ... See more keywords
Characterization of follicular T helper cells and donor-specific T helper cells in renal transplant patients with de novo donor-specific HLA-antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108698
Abstract: T follicular helper (TFH) cells are a heterogeneous subset of immunocompetent T helper (TH) cells capable of augmenting B cell responses in lymphoid tissues. In transplantation, exposure to allogeneic tissue activates TFH cells increasing the… read more here.
Keywords: specific hla; helper; follicular helper; helper cells ... See more keywords
T follicular helper cells and their impact on humoral responses during pathogen and vaccine challenge.
Sign Up to like & getrecommendations! Published in 2021 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2021.11.004
Abstract: T follicular helper (Tfh) cells are essential for the establishment, maintenance and output of the germinal centre (GC) response. The transient nature of this response, and its location within secondary lymphoid tissues have hampered our… read more here.
Keywords: humoral responses; impact humoral; helper cells; helper ... See more keywords
Prohibitin 1 interacts with signal transducer and activator of transcription 3 in T-helper 17 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Immunology letters"
DOI: 10.1016/j.imlet.2019.12.008
Abstract: T-helper 17 (Th17) cells are involved in the occurrence and development of several inflammation-associated diseases. Interleukin (IL)-17, the main cytokine secreted by differentiated Th17 cells, mediates immunoreactions and plays important roles in immunological diseases, including… read more here.
Keywords: signal transducer; activator transcription; transducer activator; th17 cells ... See more keywords
Febrile Temperature Critically Controls the Differentiation and Pathogenicity of T Helper 17 Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1016/j.immuni.2020.01.006
Abstract: Fever, an evolutionarily conserved physiological response to infection, is also commonly associated with many autoimmune diseases, but its role in T cell differentiation and autoimmunity remains largely unclear. T helper 17 (Th17) cells are critical in… read more here.
Keywords: temperature; helper; differentiation; pathogenicity ... See more keywords
High-Dimensional T Helper Cell Profiling Reveals a Broad Diversity of Stably Committed Effector States and Uncovers Interlineage Relationships.
Sign Up to like & getrecommendations! Published in 2020 at "Immunity"
DOI: 10.1016/j.immuni.2020.07.001
Abstract: CD4+ T helper (Th) cells are fundamental players in immunity. Based on the expression of signature cytokines and transcription factors, several Th subsets have been defined. Th cells are thought to be far more heterogeneous… read more here.
Keywords: high dimensional; diversity; helper; effector states ... See more keywords
The dichotomous nature of T helper 17 cells
Sign Up to like & getrecommendations! Published in 2017 at "Nature Reviews Immunology"
DOI: 10.1038/nri.2017.50
Abstract: T helper 17 (TH17) cells have been extensively studied since their discovery 10 years ago, primarily because of their known pathogenic role in many inflammatory diseases. Substantial progress has been made in understanding their development,… read more here.
Keywords: dichotomous nature; helper; helper cells; nature helper ... See more keywords
Notch signaling represents an important checkpoint between follicular T-helper and canonical T-helper 2 cell fate
Sign Up to like & getrecommendations! Published in 2018 at "Mucosal immunology"
DOI: 10.1038/s41385-018-0012-9
Abstract: Type-2 immunity is regulated by two distinct CD4+ T-cell subsets. T follicular helper (Tfh) cells are required for humoral hallmarks of type-2 inflammation. T-helper type-2 (Th2) cells orchestrate type-2 inflammation in peripheral tissues, such as the… read more here.
Keywords: helper; follicular helper; notch signaling; cell fate ... See more keywords
Transcription tipping points for T follicular helper cell and T-helper 1 cell fate commitment
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-020-00554-y
Abstract: During viral infection, immune cells coordinate the induction of inflammatory responses that clear infection and humoral responses that promote protection. CD4+ T-cell differentiation sits at the center of this axis. Differentiation toward T-helper 1 (Th1)… read more here.
Keywords: transcription; cell; tfh; helper ... See more keywords
Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16625-7
Abstract: Type I interferon (IFN-I) and T helper 17 (TH17) drive pathology in neuromyelitis optica spectrum disorder (NMOSD) and in TH17-induced experimental autoimmune encephalomyelitis (TH17-EAE). This is paradoxical because the prevalent theory is that IFN-I inhibits… read more here.
Keywords: ifn; interferon; neuromyelitis optica; helper ... See more keywords