Interaction of human HelQ with DNA polymerase delta halts DNA synthesis and stimulates DNA single-strand annealing
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DOI: 10.1093/nar/gkad032
Abstract: Abstract DNA strand breaks are repaired by DNA synthesis from an exposed DNA end paired with a homologous DNA template. DNA polymerase delta (Pol δ) catalyses DNA synthesis in multiple eukaryotic DNA break repair pathways… read more here.
Keywords: dna synthesis; dna; strand annealing; helq ... See more keywords
Division of Labor by the HELQ, BLM, and FANCM Helicases during Homologous Recombination Repair in Drosophila melanogaster
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DOI: 10.3390/genes13030474
Abstract: Repair of DNA double-strand breaks by homologous recombination (HR) requires a carefully orchestrated sequence of events involving many proteins. One type of HR, synthesis-dependent strand annealing (SDSA), proceeds via the formation of a displacement loop… read more here.
Keywords: fancm; blm; helq; homologous recombination ... See more keywords