The Immunogenicity of a Novel Chimeric Hemagglutinin-Neuraminidase-Fusion Antigen from Newcastle Disease Virus by Oral Delivery of Transgenic Canola Seeds to Chickens
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Biotechnology"
DOI: 10.1007/s12033-020-00254-y
Abstract: Newcastle disease (ND) is considered as one of the most devastating infectious diseases targeting domestic birds and has considerable threat to the commercial poultry production. Two surface glycoproteins, hemagglutinin-neuraminidase (HN) and fusion (F), act as… read more here.
Keywords: canola; seed; neuraminidase fusion; hemagglutinin neuraminidase ... See more keywords
Biosensor-based epitope mapping of antibodies targeting the hemagglutinin and neuraminidase of influenza A virus.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2018.07.007
Abstract: Characterization of the epitopes on antigen recognized by monoclonal antibodies (mAb) is useful for the development of therapeutic antibodies, diagnostic tools, and vaccines. Epitope mapping also provides functional information for sequence-based repertoire analysis of antibody… read more here.
Keywords: epitope mapping; hemagglutinin neuraminidase; mapping antibodies; based epitope ... See more keywords
VaxArray for hemagglutinin and neuraminidase potency testing of influenza vaccines.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.04.048
Abstract: Practical methods to measure the potency of influenza vaccines are needed as alternatives for the standard single radial immunodiffusion (SRID) assay. VaxArray assays for influenza hemagglutinin (HA) and neuraminidase (NA) have been developed to address… read more here.
Keywords: hemagglutinin neuraminidase; influenza vaccines; potency; measured vaxarray ... See more keywords
Directed selection of amino acid changes in the influenza hemagglutinin and neuraminidase affecting protein antigenicity.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.09.005
Abstract: Influenza virus hemagglutinin (HA) and neuraminidase (NA) proteins elicit protective antibody responses and therefore, are used as targets for vaccination, especially the HA protein. However, these proteins are subject to antigenic drift, decreasing vaccine efficacy,… read more here.
Keywords: acid changes; hemagglutinin neuraminidase; amino acid; selection ... See more keywords
Hemagglutinin-Neuraminidase and fusion genes are determinants of NDV thermostability.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2018.11.013
Abstract: Newcastle disease (ND) caused by infections with virulent strains of Newcastle disease virus (NDV) continues to be a threat for poultry industry worldwide. The prospect of developing a thermostable and effective NDV vaccine is still… read more here.
Keywords: determinants ndv; hemagglutinin neuraminidase; thermostability; virus ... See more keywords
Design, Synthesis, and Antiviral Evaluation of Sialic Acid Derivatives as Inhibitors of Newcastle Disease Virus Hemagglutinin-Neuraminidase: A Translational Study on Human Parainfluenza Viruses
Sign Up to like & getrecommendations! Published in 2023 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.2c00576
Abstract: Global infections with viruses belonging to the Paramyxoviridae, such as Newcastle disease virus (NDV) or human parainfluenza viruses (hPIVs), pose a serious threat to animal and human health. NDV-HN and hPIVs-HN (HN hemagglutinin-neuraminidase) share a… read more here.
Keywords: newcastle disease; hemagglutinin neuraminidase; parainfluenza viruses; human parainfluenza ... See more keywords
Influenza A virus hemagglutinin and neuraminidase act as novel motile machinery
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DOI: 10.1038/srep45043
Abstract: Influenza A virus (IAV) membrane proteins hemagglutinin (HA) and neuraminidase (NA) are determinants of virus infectivity, transmissibility, pathogenicity, host specificity, and major antigenicity. HA binds to a virus receptor, a sialoglycoprotein or sialoglycolipid, on the… read more here.
Keywords: machinery; hemagglutinin neuraminidase; host; influenza virus ... See more keywords
Identification of a potential neutralizing linear epitope of hemagglutinin-neuraminidase in Newcastle disease virus
Sign Up to like & getrecommendations! Published in 2021 at "Virology Journal"
DOI: 10.1186/s12985-020-01483-y
Abstract: Background The hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) is a major antigen that can induce protective antibodies in poultry. However, its antigenic epitopes have not been fully elucidated. Therefore, defining the linear epitopes… read more here.
Keywords: linear epitope; hemagglutinin neuraminidase; neutralizing linear; potential neutralizing ... See more keywords
Genetic diversity and evolutionary analysis of human respirovirus type 3 strains isolated in Kenya using complete hemagglutinin-neuraminidase (HN) gene
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DOI: 10.1371/journal.pone.0229355
Abstract: Human respirovirus type 3 (HRV3) is a leading etiology of lower respiratory tract infections in young children and ranks only second to the human respiratory syncytial virus (HRSV). Despite the public health importance of HRV3,… read more here.
Keywords: human respirovirus; hemagglutinin neuraminidase; respirovirus type; strains isolated ... See more keywords
Molecular characterization of hemagglutinin-neuraminidase fragment gene of Newcastle disease virus isolated from periodically-vaccinated farms
Sign Up to like & getrecommendations! Published in 2018 at "Veterinary World"
DOI: 10.14202/vetworld.2018.657-666
Abstract: Background and Aim: Newcastle disease (ND) caused by avian paramyxovirus serotype-1 (APMV-1) is long known as an acute contagious and infectious disease of various bird species. Prior studies have acknowledged that the virus could cause… read more here.
Keywords: amino acid; hemagglutinin neuraminidase; disease; gene ... See more keywords
Antiviral Effect of Isoquercitrin against Influenza A Viral Infection via Modulating Hemagglutinin and Neuraminidase
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232113112
Abstract: Isoquercitrin (IQC) is a component abundantly present in many plants and is known to have an anti-viral effect against various viruses. In this study, we demonstrate that IQC exhibits strong anti-influenza A virus infection, and… read more here.
Keywords: hemagglutinin neuraminidase; effect; influenza viral; infection ... See more keywords