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   Articles with "hematin" as a keyword



Kinetic modelling of the hematin catalysed decolourization of Orange II solutions

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recommendations! Published in 2017 at "Chemical Engineering Science"

DOI: 10.1016/j.ces.2016.11.049

Abstract: Abstract A mathematical description of the kinetics of the hematin catalysed decolourization reaction of Orange II alkaline solutions was constructed and validated under the assumption that hematin mimics the action of peroxidases. The clean oxidant… read more here.

Keywords: hematin catalysed; rate; catalysed decolourization; hematin ... See more keywords

Plasmonic SERS Biosensor Based on Multibranched Gold Nanoparticles Embedded in Polydimethylsiloxane for Quantification of Hematin in Human Erythrocytes.

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recommendations! Published in 2020 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.0c03921

Abstract: This work reports a plasmonic surface-enhanced Raman scattering (SERS) biosensor that allows for quantitative analysis of hematin in erythrocytes without the need of separating it from hemoglobin (Hb). The biosensor exploits the tunable localized surface… read more here.

Keywords: gold nanoparticles; sers biosensor; multibranched gold; embedded polydimethylsiloxane ... See more keywords

Tafenoquine Disrupts Intraerythrocytic Stages of Malaria Parasites by Inhibiting Nonclassical Pathways of β-Hematin Nucleation and Growth.

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recommendations! Published in 2025 at "Biochemistry"

DOI: 10.1021/acs.biochem.5c00164

Abstract: The rise in malaria resistance to multiple classes of drugs has led to an alarming increase in the number of cases and fatalities worldwide. Tafenoquine (TQ), an antimalarial approved by the Food and Drug Administration… read more here.

Keywords: hematin; disrupts intraerythrocytic; tafenoquine disrupts; stages malaria ... See more keywords

Structuring of Organic Solvents at Solid Interfaces and Ramifications for Antimalarial Adsorption on β-Hematin Crystals.

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recommendations! Published in 2018 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.8b08579

Abstract: A critical aspect of material synthesis is solvent structuring at solid-liquid interfaces, which can impact the adsorption of solute and growth modifiers on an underlying substrate. In general, the impact of solvent structuring on molecular… read more here.

Keywords: hematin crystals; adsorption; organic solvents; structuring organic ... See more keywords

Glutathione–Hemin/Hematin Adduct Formation to Disintegrate Cytotoxic Oxidant Hemin/Hematin in Human K562 Cells and Red Blood Cells’ Hemolysates: Impact of Glutathione on the Hemolytic Disorders and Homeostasis

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recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11101959

Abstract: Hemin, an oxidized form of heme, acts as potent oxidant to regulate glutathione (GSH) content in pro-erythroid K562 nucleated cells, via activation of the KEAP1/NRF2 defensive signaling pathway. Moreover, GSH, as an essential metabolite, is… read more here.

Keywords: k562 cells; gsh; hemin hematin; hemin ... See more keywords