The DNA methylation landscape of hematological malignancies: an update
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12744
Abstract: The rapid advances in high‐throughput sequencing technologies have made it more evident that epigenetic modifications orchestrate a plethora of complex biological processes. During the last decade, we have gained significant knowledge about a wide range… read more here.
Keywords: methylation; landscape hematological; methylation landscape; hematological malignancies ... See more keywords
Natural killer cells: Innate immune system as a part of adaptive immunotherapy in hematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26529
Abstract: Natural killer (NK) cells are part of a phylogenetically old defense system, which is characterized by its strong cytolytic function against physiologically stressed cells such as tumor cells and virus‐infected cells. Their use in the… read more here.
Keywords: system; natural killer; killer cells; hematological malignancies ... See more keywords
Chimeric antigen receptor T (CAR‐T) cells: Novel cell therapy for hematological malignancies
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5551
Abstract: Over the last decade, the emergence of several novel therapeutic approaches has changed the therapeutic perspective of human malignancies. Adoptive immunotherapy through chimeric antigen receptor T cell (CAR‐T), which includes the engineering of T cells… read more here.
Keywords: cell; antigen receptor; chimeric antigen; cell therapy ... See more keywords
COVID‐19 in patients with hematological malignancies: Considering the role of tyrosine kinase inhibitors
Sign Up to like & getrecommendations! Published in 2021 at "Cancer"
DOI: 10.1002/cncr.33432
Abstract: In an article previously published in Cancer, Cattaneo et al analyzed a cohort of patients with coronavirus disease 2019 (COVID-19) and hematological malignancies in March 2020, and they highlighted that subjects with chronic myeloid leukemia… read more here.
Keywords: kinase inhibitors; covid; role tyrosine; role ... See more keywords
Standardization of Flow Cytometric Immunophenotyping for Hematological Malignancies: The FranceFlow Group Experience
Sign Up to like & getrecommendations! Published in 2019 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23844
Abstract: Flow cytometry is broadly used for the identification, characterization, and monitoring of hematological malignancies. However, the use of clinical flow cytometry is restricted by its lack of reproducibility across multiple centers. Since 2006, the EuroFlow… read more here.
Keywords: hematology; group; franceflow group; hematological malignancies ... See more keywords
Recent advances in chimeric antigen receptor natural killer cell therapy for overcoming intractable hematological malignancies
Sign Up to like & getrecommendations! Published in 2020 at "Hematological Oncology"
DOI: 10.1002/hon.2802
Abstract: Natural killer (NK) cells have a potent cytotoxic activity against leukemia and lymphoma without recognition of human leukocyte antigen (HLA) molecules. Chimeric antigen receptor‐engineered NK cells (CAR‐NK cells) can be produced from the NK92 cell… read more here.
Keywords: therapy; natural killer; antigen; hematological malignancies ... See more keywords
Trimethoprim‐sulfamethoxazole as Pneumocystis jiroveci pneumonia prevention in patients undergoing methotrexate therapy for hematological malignancies: A review of the literature
Sign Up to like & getrecommendations! Published in 2020 at "Hematological Oncology"
DOI: 10.1002/hon.2823
Abstract: Methotrexate is a cytotoxic agent that is commonly used to treat autoimmune diseases, and both solid and hematological malignancies. Drug interactions are of particular concern during methotrexate therapy, as they have the potential to alter… read more here.
Keywords: methotrexate; patients undergoing; trimethoprim sulfamethoxazole; methotrexate therapy ... See more keywords
Secondary infections worsen the outcome of COVID‐19 in patients with hematological malignancies: A report from the ITA‐HEMA‐COV
Sign Up to like & getrecommendations! Published in 2022 at "Hematological Oncology"
DOI: 10.1002/hon.3048
Abstract: The impact of secondary infections (SI) on COVID‐19 outcome in patients with hematological malignancies (HM) is scarcely documented. To evaluate incidence, clinical characteristics, and outcome of SI, we analyzed the microbiologically documented SI in a… read more here.
Keywords: secondary infections; covid; hematological malignancies; infections worsen ... See more keywords
LACK OF EFFICACY OF CONVALESCENT PLASMA IN COVID-19 PATIENTS WITH CONCOMITANT HEMATOLOGICAL MALIGNANCIES AN ITALIAN RETROSPECTIVE STUDY.
Sign Up to like & getrecommendations! Published in 2022 at "Hematological oncology"
DOI: 10.1002/hon.3060
Abstract: A multicenter retrospective study was designed to assess clinical outcome of COVID-19 in patients with hematological malignancies (HM) following treatment with anti-SARS-CoV-2 convalescent plasma (CP) or standard of care therapy. To this aim, a propensity… read more here.
Keywords: covid patients; retrospective study; covid; hematological malignancies ... See more keywords
Alcohol consumption and risk of hematological malignancies: A meta‐analysis of prospective studies
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DOI: 10.1002/ijc.31330
Abstract: Current convincing evidence suggests that alcohol intake increases the risk of several carcinomas, which might subsequently lead to a recommendation toward limiting alcohol consumption. However, there are accumulating data worth meta‐analyzing that show a different… read more here.
Keywords: risk; alcohol consumption; risk hematological; hematological malignancies ... See more keywords
Anthropometric characteristics, physical activity and risk of hematological malignancies: A systematic review and meta‐analysis of cohort studies
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Cancer"
DOI: 10.1002/ijc.32109
Abstract: Overweight/obesity, adult attained height and physical activity are possible risk factors for hematological malignancies. This meta‐analysis aims to evaluate the associations between these factors and hematological cancer risk in adults. Eligible cohort studies were sought… read more here.
Keywords: risk; physical activity; hematological malignancies; leukemia ... See more keywords