CpG and Rutin Co‐Loaded DNA Tetrahedra for Targeted Therapy of Intracerebral Hemorrhage: Synergistic Hematoma Clearance and Neuroinflammation Inhibition
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202403469
Abstract: Intracerebral hemorrhage (ICH) presents a formidable challenge due to its high mortality and disability rates, primarily attributed to cerebral hematoma formation and ensuing neuroinflammation. Swift hematoma removal is paramount for prognosis, yet existing interventions carry… read more here.
Keywords: neuroinflammation; intracerebral hemorrhage; hematoma; hematoma clearance ... See more keywords
Magnetic Targeting Nanocarriers Combined with Focusing Ultrasound for Enhanced Intracerebral Hemorrhage Therapy.
Sign Up to like & getrecommendations! Published in 2023 at "Small"
DOI: 10.1002/smll.202206982
Abstract: Intracerebral hemorrhage (ICH) remains a significant cause of morbidity and mortality around the world, and surgery is still the most direct and effective way to remove ICH. However, the potential risks brought by surgery, such… read more here.
Keywords: hematoma clearance; hematoma; magnetic targeting; focusing ultrasound ... See more keywords
CD47 blocking antibody accelerates hematoma clearance and alleviates hydrocephalus after experimental intraventricular hemorrhage
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Disease"
DOI: 10.1016/j.nbd.2021.105384
Abstract: Background CD47, a glycoprotein on red blood cell membranes, inhibits phagocytosis via interaction with signal regulatory protein α on phagocytes. Our previous research has demonstrated that blocking CD47 accelerates hematoma clearance and reduces brain injury… read more here.
Keywords: cd47 blocking; cd47; blocking antibody; hematoma clearance ... See more keywords
Response by Hua et al to Letter Regarding Article, "Enhancement of Hematoma Clearance With CD47 Blocking Antibody in Experimental Intracerebral Hemorrhage".
Sign Up to like & getrecommendations! Published in 2019 at "Stroke"
DOI: 10.1161/strokeaha.119.026620
Abstract: In Response: We thank Dr Chen et al for their interest in our article. We have demonstrated that CD47 blocking antibody can enhance hematoma clearance through activation of microglia/macrophages and improve functional outcomes in a… read more here.
Keywords: blocking antibody; cd47; antibody; hematoma clearance ... See more keywords
Vitamin D Enhances Hematoma Clearance and Neurologic Recovery in Intracerebral Hemorrhage
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.037769
Abstract: Background: Erythrophagocytosis by reparative monocyte-derived macrophage contributes to hematoma clearance and neurological recovery after intracerebral hemorrhage (ICH). Vitamin D (VitD) is a neuroprotective hormone and regulates the differentiation of monocyte-derived macrophage from monocytes. In this… read more here.
Keywords: clearance; hematoma clearance; recovery intracerebral; macrophage ... See more keywords
Neuroendoscopic Surgical Treatment of Hypertensive Brainstem Hemorrhage.
Sign Up to like & getrecommendations! Published in 2024 at "Turkish neurosurgery"
DOI: 10.5137/1019-5149.jtn.47812-24.2
Abstract: AIM To investigate the clinical effect of neuroendoscopic surgery on 15 patients with hypertensive brainstem hemorrhage (HBSH). MATERIAL AND METHODS A retrospective analysis was conducted on the clinical data collected from 15 patients with HBSH… read more here.
Keywords: hypertensive brainstem; treatment; rate; hematoma clearance ... See more keywords