StemRegenin 1 Mitigates Radiation-Mediated Hematopoietic Injury by Modulating Radioresponse of Hematopoietic Stem/Progenitor Cells
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DOI: 10.3390/biomedicines11030824
Abstract: Hematopoietic injury resulting from the damage of hematopoietic stem/progenitor cells (HSPCs) can be induced by either nuclear accident or radiotherapy. Radiomitigation of HSPCs is critical for the development of medical countermeasure agents. StemRegenin 1 (SR1)… read more here.
Keywords: stem progenitor; hematopoietic stem; radiation; progenitor cells ... See more keywords
Gamma-Tocotrienol Modulates Total-Body Irradiation-Induced Hematopoietic Injury in a Nonhuman Primate Model
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DOI: 10.3390/ijms232416170
Abstract: Radiation exposure causes acute damage to hematopoietic and immune cells. To date, there are no radioprotectors available to mitigate hematopoietic injury after radiation exposure. Gamma-tocotrienol (GT3) has demonstrated promising radioprotective efficacy in the mouse and… read more here.
Keywords: nonhuman primate; gamma tocotrienol; recovery; hematopoietic injury ... See more keywords