Intrafemoral Delivery of Hematopoietic Progenitors.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1425-9_13
Abstract: Hematopoiesis is a central process and is essential for the replenishment of short-lived leukocytes such as neutrophils. However, the molecular events underlining the developmental transition of quiescent hematopoietic stem cells into downstream progenitors and mature… read more here.
Keywords: delivery; delivery hematopoietic; hematopoietic progenitors; biology ... See more keywords
An in vitro platform supports generation of human innate lymphoid cells from CD34+ hematopoietic progenitors that recapitulate ex vivo identity.
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.07.019
Abstract: Innate lymphoid cells (ILCs) are critical effectors of innate immunity and inflammation, whose development and activation pathways make for attractive therapeutic targets. However, human ILC generation has not been systematically explored, and previous in vitro investigations… read more here.
Keywords: innate lymphoid; hematopoietic progenitors; lymphoid cells; cd34 hematopoietic ... See more keywords
EVI2B is a C/EBPα target gene required for granulocytic differentiation and functionality of hematopoietic progenitors
Sign Up to like & getrecommendations! Published in 2017 at "Cell Death and Differentiation"
DOI: 10.1038/cdd.2017.6
Abstract: Development of hematopoietic populations through the process of differentiation is critical for proper hematopoiesis. The transcription factor CCAAT/enhancer binding protein alpha (C/EBPα) is a master regulator of myeloid differentiation, and the identification of C/EBPα target… read more here.
Keywords: functionality; target; hematopoietic progenitors; differentiation ... See more keywords
GATA1 controls numbers of hematopoietic progenitors and their response to autoimmune neuroinflammation
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022008234
Abstract: Key Points • ΔdblGATA mice are resistant to EAE but not due to their lack of eosinophils.• GATA1 regulates numbers of HSPCs in the BM, and the ΔdblGATA mutation causes a functional deficit during inflammation. read more here.
Keywords: numbers hematopoietic; gata1 controls; response autoimmune; controls numbers ... See more keywords
Genetic engineering of Hoxb8-immortalized hematopoietic progenitors – a potent tool to study macrophage tissue migration
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.236703
Abstract: ABSTRACT Tumor-associated macrophages (TAMs) are detrimental in most cancers. Controlling their recruitment is thus potentially therapeutic. We previously found that TAMs perform protease-dependent mesenchymal migration in cancer, while macrophages perform amoeboid migration in other tissues.… read more here.
Keywords: hoxb8 immortalized; immortalized hematopoietic; potent tool; hematopoietic progenitors ... See more keywords
Editorial: The Role of Hematopoietic Progenitors in Immune Regulation and Memory
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.789139
Abstract: 1 Université de Paris, INSERM U1151, CNRS UMR8253, Institut Necker Enfants Malades, Paris, France, 2 Department of Medical Oncology and Hematology, University of Zurich and University Hospital Zurich, Zurich, Switzerland, 3 International Center for Type… read more here.
Keywords: editorial role; hematopoietic progenitors; progenitors immune; regulation memory ... See more keywords
Impact of Double-Stranded RNA Internalization on Hematopoietic Progenitors and Krebs-2 Cells and Mechanism
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054858
Abstract: It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective and radiotherapeutic effects. The experiments conducted in this study directly demonstrated that dsRNA was delivered into the cell in its native form and that it… read more here.
Keywords: double stranded; cell; stranded rna; hematopoietic progenitors ... See more keywords