Amentoflavone protects the hematopoietic system of mice against γ-irradiation.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of pharmacal research"
DOI: 10.1007/s12272-019-01187-0
Abstract: Some flavonoids have been shown to exhibit good antioxidant activity and protect mice from damage induced by radiation. Amentoflavone (AMF), a biflavonoid derived from the traditional herb-Selaginella tamariscina, has been reported to have antioxidant properties.… read more here.
Keywords: irradiation; system; hematopoietic system; amentoflavone ... See more keywords
3113 – HEMATOPOIETIC STEM CELL DYNAMICS IN A NON-IRRADIATED TRANSPLANTATION MODEL
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Hematology"
DOI: 10.1016/j.exphem.2020.09.123
Abstract: Hematopoietic stem cells (HSCs) are defined as the cells that have the ability of both multi-potency and self-renewal. This property of HSCs has traditionally been characterized by transplantation assays where the donor HSCs are transferred… read more here.
Keywords: hscs; model; transplantation; hematopoietic system ... See more keywords
Real versus simulated galactic cosmic radiation for investigating cancer risk in the hematopoietic system - are we comparing apples to apples?
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences in space research"
DOI: 10.1016/j.lssr.2021.01.001
Abstract: Deep space exploration missions need strategies to mitigate the potentially harmful exposure to galactic cosmic radiation. This form of radiation can cause significant damage to biological systems and organisms, which include radiation-induced carcinogenesis in the… read more here.
Keywords: space; hematopoietic system; cancer risk; galactic cosmic ... See more keywords
Internal m6A and m7G RNA modifications in hematopoietic system and acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2024 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000003073
Abstract: Abstract Epitranscriptomics focuses on the RNA-modification-mediated post-transcriptional regulation of gene expression. The past decade has witnessed tremendous progress in our understanding of the landscapes and biological functions of RNA modifications, as prompted by the emergence… read more here.
Keywords: system; acute myeloid; hematopoietic system; rna modifications ... See more keywords
Assembling the layers of the hematopoietic system: A window of opportunity for thymopoiesis in the embryo
Sign Up to like & getrecommendations! Published in 2023 at "Immunological Reviews"
DOI: 10.1111/imr.13187
Abstract: During embryonic development, several independent generations of hematopoietic cells were identified. They occur in the yolk sac and the intra‐embryonic major arteries, in a narrow window of development. They arise sequentially, starting with primitive erythrocytes… read more here.
Keywords: system; hematopoietic system; layers hematopoietic; assembling layers ... See more keywords
Autophagy and Its Lineage-Specific Roles in the Hematopoietic System
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/8257217
Abstract: Autophagy is a dynamic process that regulates the selective and nonselective degradation of cytoplasmic components, such as damaged organelles and protein aggregates inside lysosomes to maintain tissue homeostasis. Different types of autophagy including macroautophagy, microautophagy,… read more here.
Keywords: specific roles; autophagy lineage; lineage specific; hematopoietic system ... See more keywords
Engrafted JAK2V617F Clone Hijacks Resident Non-Mutated Hematopoietic System to Drive Myeloproliferative Neoplasm
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-208312
Abstract: JAK2V617F is a major driver mutation in myeloproliferative neoplasms (MPN) and JAK2 inhibitors can alleviate the disease burden for patients with MPN. However, questions remain about the mechanistic role of JAK2V617F in driving the pleiotropy… read more here.
Keywords: jak2v617f; clone; hematopoietic system; jak2v617f clone ... See more keywords
Dynamic rRNA Methylation Regulates Translation in the Hematopoietic System and is Essential for Stem Cell Fitness.
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood.2024028300
Abstract: Self-renewal and differentiation are at the basis of hematopoiesis. While it is known that tight regulation of translation is vital for hematopoietic stem cells' (HSCs) biology, the mechanisms underlying translation regulation across the hematopoietic system… read more here.
Keywords: differentiation; hematopoietic system; translation; cell ... See more keywords
Characterization of the Drosophila Adult Hematopoietic System Reveals a Rare Cell Population With Differentiation and Proliferation Potential
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.739357
Abstract: While many studies have described Drosophila embryonic and larval blood cells, the hematopoietic system of the imago remains poorly characterized and conflicting data have been published concerning adult hematopoiesis. Using a combination of blood cell… read more here.
Keywords: hematopoietic system; blood; blood cells; cell ... See more keywords
DNA damage and repair in the hematopoietic system
Sign Up to like & getrecommendations! Published in 2022 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.3724/abbs.2022053
Abstract: Although hematopoietic stem cells (HSCs) in the bone marrow are in a state of quiescence, they harbor the self-renewal capacity and the pluripotency to differentiate into mature blood cells when needed, which is key to… read more here.
Keywords: hscs; hematopoietic system; damage; dna damage ... See more keywords