Sex and Circadian Timing Modulate Oxaliplatin Hematological and Hematopoietic Toxicities
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DOI: 10.3390/pharmaceutics14112465
Abstract: Oxaliplatin was nearly twice as hematotoxic, with optimal circadian timing differing by 6 h, in women as compared to men with colorectal cancers. Hence, we investigated sex- and timing-related determinants of oxaliplatin hematopoietic toxicities in… read more here.
Keywords: timing; circadian rhythms; sex; hematopoietic toxicities ... See more keywords