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   Articles with "heme binding" as a keyword



The Cys‐Pro motifs in the intrinsically disordered regions of the transcription factor BACH1 mediate distinct and overlapping functions upon heme binding

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14338

Abstract: The function of the transcription factor BACH1 is regulated by heme binding to multiple Cys‐Pro (CP) motifs within its intrinsically disordered regions. Here, biochemical analyses were conducted to reveal the individual functional roles of the… read more here.

Keywords: cys pro; heme; heme binding; factor bach1 ... See more keywords

Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties

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recommendations! Published in 2022 at "FEBS Letters"

DOI: 10.1002/1873-3468.14446

Abstract: Mtb8.4, a secretory T‐cell antigen of Mycobacterium tuberculosis, is important for providing an antigen‐specific immune response. In this study, we showed Mtb8.4 to have both heme‐binding and fibril‐forming properties, using experimental and in silico methods.… read more here.

Keywords: heme; heme binding; mtb8 heme; mtb8 ... See more keywords

Computational Insights Into Antimicrobial Peptide‐Enhanced Dental Resin Composites: Targeting Porphyromonas gingivalis Heme‐Binding Proteins and Biofilms

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recommendations! Published in 2025 at "MicrobiologyOpen"

DOI: 10.1002/mbo3.70184

Abstract: The research aimed at investigating the antibacterial potential of dental resin composites when combined with various antimicrobial peptides (AMPs) against Porphyromonas gingivalis heme‐binding proteins, which are associated with biofilm‐related infections in restorative dentistry. A multistage… read more here.

Keywords: gingivalis heme; resin composites; binding proteins; heme binding ... See more keywords

Heme-binding of bovine lactoferrin: the potential presence of a heme-binding capacity in an ancestral transferrin gene

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recommendations! Published in 2017 at "BioMetals"

DOI: 10.1007/s10534-017-0075-1

Abstract: Lactoferrin (Lf) and transferrin (Tf) are iron-binding proteins that can bind various metal ions. This study demonstrates the heme-binding activity of bovine Lf and Tf using biotinylated hemin. When both proteins were coated on separate… read more here.

Keywords: heme; bovine; biotinylated hemin; heme binding ... See more keywords

Precise determination of heme binding affinity in proteins.

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recommendations! Published in 2019 at "Analytical biochemistry"

DOI: 10.1016/j.ab.2019.02.021

Abstract: Accumulating evidence suggests a new role for cellular heme as a signalling molecule, in which interactions with target proteins are more transient than found with traditionally-defined hemoproteins. To study this role, a precise method is… read more here.

Keywords: protein; precise determination; heme binding; binding affinity ... See more keywords

Dual role of the active-center cysteine in human peroxiredoxin 1: Peroxidase activity and heme binding.

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recommendations! Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.01.034

Abstract: HBP23, a 23-kDa heme-binding protein identified in rats, is a member of the peroxiredoxin (Prx) family, the primary peroxidases involved in hydrogen peroxide catabolism. Although HBP23 has a characteristic Cys-Pro heme-binding motif, the significance of… read more here.

Keywords: heme; prx1; heme binding; peroxidase activity ... See more keywords

Synthesis, antimalarial activity, heme binding and docking studies of N-substituted 4-aminoquinoline-pyrimidine molecular hybrids.

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recommendations! Published in 2017 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2017.02.024

Abstract: A series of novel N-substituted 4-aminoquinoline-pyrimidine hybrids have been synthesized via simple and economic route and evaluated for their antimalarial activity. Most compounds showed potent antimalarial activity against both CQ-sensitive and CQ-resistant strains with high… read more here.

Keywords: substituted aminoquinoline; aminoquinoline pyrimidine; antimalarial activity; activity ... See more keywords

A single mutation converts Alr5027 from cyanobacteria Nostoc sp. PCC 7120 to a heme-binding protein with heme-degrading ability.

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recommendations! Published in 2019 at "Journal of inorganic biochemistry"

DOI: 10.1016/j.jinorgbio.2019.110916

Abstract: HutZ from Vibrio cholerae (VcHutZ) is a dimeric protein that catalyzes oxygen-dependent degradation of heme. The reaction mechanism is the same as that of canonical heme oxygenase (HO), but the structure of HutZ is quite… read more here.

Keywords: degradation; heme; binding protein; ability ... See more keywords

Design and Function of α-Helix-Rich, Heme-Binding Peptide Materials.

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recommendations! Published in 2024 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.4c00049

Abstract: Peptide materials often employ short peptides that self-assemble into unique nanoscale architectures and have been employed across many fields relevant to medicine and energy. A majority of peptide materials are high in β-sheet, secondary structure… read more here.

Keywords: binding peptide; function; helix; heme ... See more keywords

A rice SOUL family heme-binding protein REAC1 enhances the antioxidative capacity of C. elegans through modulation of ROS-related gene expression

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-95254-w

Abstract: The development and identification of beneficial components from crop resources are vital for individuals, especially the elderly, as they are capable of facilitating health. Red rice is widely consumed and possesses potential therapeutic effects to… read more here.

Keywords: rice; antioxidative capacity; capacity elegans; binding protein ... See more keywords

Identification of a secretory heme-binding protein from Nocardia seriolae involved in cell apoptosis.

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recommendations! Published in 2022 at "Journal of fish diseases"

DOI: 10.1111/jfd.13654

Abstract: According to the whole-genome bioinformatics analysis, a heme-binding protein from Nocardia seriolae (HBP) was found. HBP was predicted to be a bacterial secretory protein, located at mitochondrial membrane in eukaryotic cells and have a similar protein… read more here.

Keywords: heme binding; binding protein; apoptosis; cell apoptosis ... See more keywords