Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction
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DOI: 10.1073/pnas.2116708119
Abstract: Significance During infection, the human pathogen Staphylococcus aureus expresses a surface-exposed receptor, Iron surface determinant B (IsdB), that captures free human hemoglobin (Hb) and removes heme to retrieve iron, an essential nutrient for bacterial proliferation… read more here.
Keywords: heme; heme extraction; human hemoglobin; isdb ... See more keywords