Targeting heme-oxidized soluble guanylate cyclase to promote osteoblast function.
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DOI: 10.1016/j.drudis.2019.12.004
Abstract: The enzyme soluble guanylate cyclase (sGC) plays an essential part in the nitric oxide (NO) signaling pathway by binding to the prosthetic heme group; thereby catalyzing the synthesis of cyclic guanosine monophosphate (cGMP)-dependent protein kinases.… read more here.
Keywords: osteoblast function; heme oxidized; soluble guanylate; guanylate cyclase ... See more keywords