Hemin provides protection against lead neurotoxicity through heme oxygenase 1/carbon monoxide activation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3646
Abstract: The neurotoxicity of lead (Pb) is well established, and oxidative stress is strongly associated with Pb‐induced neurotoxicity. Heme oxygenase 1 (HO‐1) is an important antioxidative enzyme for protection against oxidative stress in many disease models.… read more here.
Keywords: protection; hemin; neurotoxicity; carbon monoxide ... See more keywords
Effects of Molecular Crowding on G-Quadruplex-hemin Mediated Peroxidase Activity
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Research in Chinese Universities"
DOI: 10.1007/s40242-020-0018-1
Abstract: The concentration of macromolecules in cells can reach up to 50–400 mg/mL. They occupy 40%(volume fraction) of the whole cellar space, known as molecular crowding. The diluted solution condition in vitro is different from the… read more here.
Keywords: condition; peroxidase activity; hemin; molecular crowding ... See more keywords
An ultrasensitive aptasensor for hemin and hemoglobin based on signal amplification via electrocatalytic oxygen reduction.
Sign Up to like & getrecommendations! Published in 2017 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2016.11.016
Abstract: The present study aims at the fabrication of a novel electrochemical aptasensor, Ap-GA-AMSN-GCE, for the label-free determination of hemin and hemoglobin (Hb). Basically, the electrochemical reduction current of hemin or Hb incubated on Ap-GA-AMSN-GCE in… read more here.
Keywords: oxygen; aptasensor; hemin hemoglobin; hemin ... See more keywords
Characteristics of Treponema denticola lipooligosaccharide in presence of hemin and quorum-sensing molecule.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2021.105062
Abstract: OBJECTIVES The study aimed to examine the diverse bioactivity of lipooligosaccharide extracted from T. denticola cultured in the presence of hemin and quorum-sensing inhibitor. DESIGN T. denticola was cultured in the presence or absence hemin… read more here.
Keywords: presence hemin; forsythia lipopolysaccharide; hemin quorum; presence ... See more keywords
Non‐immunological toxicological mechanisms of metamizole‐associated neutropenia in HL60 cells
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2019.01.011
Abstract: Graphical abstract Figure. No caption available. &NA; Metamizole is an analgesic and antipyretic, but can cause neutropenia and agranulocytosis. We investigated the toxicity of the metabolites N‐methyl‐4‐aminoantipyrine (MAA), 4‐aminoantipyrine (AA), N‐formyl‐4‐aminoantipyrine (FAA) and N‐acetyl‐4‐aminoantipyrine (AAA)… read more here.
Keywords: metamizole associated; aminoantipyrine; hemin; hl60 cells ... See more keywords
Deferoxamine therapy reduces brain hemin accumulation after intracerebral hemorrhage in piglets
Sign Up to like & getrecommendations! Published in 2019 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2019.05.003
Abstract: Hemopexin (Hpx) is critical for hemin scavenging after the erythrocyte lysis that occurs following intracerebral hemorrhage (ICH). Low-density lipoprotein receptor-related protein-1 (LRP1, also called CD91) is an important receptor through which the hemin-Hpx complex can… read more here.
Keywords: hpx cd91; brain; hemin; tissue ... See more keywords
Membraneless biofuel cells using new cathodic catalyst including hemin bonded with amine functionalized carbon nanotube and glucose oxidase sandwiched by poly(dimethyl-diallylammonium chloride)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Industrial and Engineering Chemistry"
DOI: 10.1016/j.jiec.2020.04.010
Abstract: Abstract A new cathodic catalyst is developed for improving the performance of membraneless enzymatic biofuel cell (EBC) by enhancing overall oxygen reduction reaction (ORR). In this catalyst, both hemin and glucose oxidase (GOx) are considered… read more here.
Keywords: gox; cathodic catalyst; membraneless; hemin ... See more keywords
Dual role of hemin in Pt nanoparticle deposition on carbon nanotubes for methanol electro-oxidation and oxygen reduction
Sign Up to like & getrecommendations! Published in 2019 at "Materials Letters"
DOI: 10.1016/j.matlet.2019.01.073
Abstract: Abstract This paper presents a novel and simple non-covalent method to synthesize a double-cladding coaxial structured hybrid by depositing Pt nanoparticles on hemin-coated multi-walled carbon nanotubes (MWCNTs). The Pt nanoparticles cooperated with hemin can be… read more here.
Keywords: methanol electro; oxygen reduction; oxidation oxygen; oxidation ... See more keywords
Fate of iron during hydrothermal liquefaction of hemin
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Supercritical Fluids"
DOI: 10.1016/j.supflu.2019.104705
Abstract: Abstract Hemin, an iron porphyrin, was used as a model compound to study the fate of iron during hydrothermal liquefaction (HTL). Hemin decomposed hydrothermally and produced an oil-phase with appreciable iron content only at temperatures… read more here.
Keywords: iron hydrothermal; fate iron; hemin; iron ... See more keywords
Ferric heme b in aqueous micellar and vesicular systems: state-of-the-art and challenges
Sign Up to like & getrecommendations! Published in 2023 at "Quarterly Reviews of Biophysics"
DOI: 10.1017/s0033583522000130
Abstract: Abstract Ferric heme b (= ferric protoporphyrin IX = hemin) is an important prosthetic group of different types of enzymes, including the intensively investigated and widely applied horseradish peroxidase (HRP). In HRP, hemin is present… read more here.
Keywords: micellar vesicular; aqueous micellar; hemin; vesicular systems ... See more keywords
Highly Sensitive Biosensing Applications of a Magnetically Immobilizable Covalent G-Quadruplex-Hemin DNAzyme Catalytic System.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c04842
Abstract: G-quadruplex/hemin (G4/hemin) DNAzymes are biosensing systems, but their application remains limited by an overall low activity and a rather high level of unwarranted background reactions. Here, these issues were addressed through the rational design of… read more here.
Keywords: system; dnazyme; hemin; quadruplex hemin ... See more keywords