Intrastriatal Chromospheres’ Transplant Reduces Nociception in Hemiparkinsonian Rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2017.08.052
Abstract: The present study evaluates the possible antinociceptive effect of chromosphere transplants in rats injected with 6-hydroxydopamine (6-OHDA), a model of Parkinson's disease. Male adult Wistar rats received 40μg/0.5μl of 6-OHDA or 0.5μl of vehicle into… read more here.
Keywords: chromospheres transplant; reduces nociception; intrastriatal chromospheres; transplant reduces ... See more keywords
The Protein-Rich Fraction from Spirulina platensis Exerts Neuroprotection in Hemiparkinsonian Rats by Decreasing Brain Inflammatory-Related Enzymes and Glial Fibrillary Acidic Protein Expressions.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal food"
DOI: 10.1089/jmf.2021.0100
Abstract: Spirulina platensis is a cyanobacterium with high protein content and presenting neuroprotective effects. Now, we studied a protein-enriched fraction (SPF), on behavior, neurochemical and immunohistochemical (IHC) assays in hemiparkinsonian rats, distributed into the groups: SO… read more here.
Keywords: brain; hemiparkinsonian rats; spirulina platensis; fraction ... See more keywords
5-(4-Hydroxy-3-dimethoxybenzylidene)-thiazolidinone improves motor functions and exerts antioxidant potential in hemiparkinsonian rats
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000712
Abstract: Our previous study demonstrated that 5-(4-hydroxy-3-dimethoxybenzylidene)-thiazolidinone (RD-1), one of rhodamine derivatives, significantly improves motor function in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model and could minimize mitochondrial impairment, which is a potential therapeutic target to slow down the… read more here.
Keywords: motor functions; improves motor; dimethoxybenzylidene thiazolidinone; motor ... See more keywords
Effects of L-dopa on expression of prolactin and synaptotagmin IV in 17-beta-estradiol-induced prolactinomas of ovariectomized hemiparkinsonian rats.
Sign Up to like & getrecommendations! Published in 2021 at "Bosnian journal of basic medical sciences"
DOI: 10.17305/bjbms.2021.5491
Abstract: Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. Dopamine precursor L-dopa is used as the first-line treatment for PD. Evidence suggests neuroprotective effects of… read more here.
Keywords: dopa expression; ovariectomized hemiparkinsonian; expression; prl ... See more keywords
Roles of Motor Cortex Neuron Classes in Reach-Related Modulation for Hemiparkinsonian Rats
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.645849
Abstract: Disruption of the function of the primary motor cortex (M1) is thought to play a critical role in motor dysfunction in Parkinson’s disease (PD). Detailed information regarding the specific aspects of M1 circuits that become… read more here.
Keywords: neuron; pyramidal neurons; motor; motor cortex ... See more keywords
Intrapallidal injection of cannabidiol or a selective GPR55 antagonist decreases motor asymmetry and improves fine motor skills in hemiparkinsonian rats
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.945836
Abstract: Cannabidiol (CBD) presents antiparkinsonian properties and neuromodulatory effects, possibly due to the pleiotropic activity caused at multiple molecular targets. Recently, the GPR55 receptor has emerged as a molecular target of CBD. Interestingly, GPR55 mRNA is… read more here.
Keywords: motor skills; motor; lesion; hemiparkinsonian rats ... See more keywords