HGG-31. GENOMIC CORRELATIONS WITH HEMORRHAGE RISK IN PEDIATRIC PATIENTS WITH DIFFUSE HEMISPHERIC GLIOMA
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DOI: 10.1093/neuonc/noae064.315
Abstract: Abstract BACKGROUND Pediatric diffuse hemispheric glioma (DHG) is a histone-mutated (H3.3G34R/V) high-grade glioma with poor prognosis. Clinical observation and previous reports have identified that a subset of patients present with tumor-associated hemorrhage. Here, we present… read more here.
Keywords: hemispheric glioma; risk; diffuse hemispheric; hemorrhage ... See more keywords
The clinical and molecular landscape of diffuse hemispheric glioma, H3 G34-mutant
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DOI: 10.1093/neuonc/noaf015
Abstract: Abstract Background Diffuse hemispheric glioma, histone 3 (H3) G34-mutant, has been newly defined in the 2021 World Health Organization (WHO) classification of central nervous system tumors. Here we sought to define the prognostic roles of… read more here.
Keywords: hemispheric glioma; molecular landscape; diffuse hemispheric; g34 mutant ... See more keywords
Neuroimaging features of diffuse hemispheric glioma, H3 G34‐mutant: A case series and systematic review
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DOI: 10.1111/jon.12939
Abstract: Diffuse hemispheric gliomas, H3 G34‐mutant (DHGs‐G34m), are newly recognized malignant brain tumors characterized by histone gene mutations. However, the neuroradiologic characteristics of these tumors require elucidation. We reviewed the demographic, clinical, and neuroradiological features of… read more here.
Keywords: g34 mutant; features diffuse; hemispheric glioma; diffuse hemispheric ... See more keywords
Diffuse Hemispheric Glioma, H3 G34‐Mutant With Prominent Perivascular Invasion in a Middle‐Aged Man: A Case Report and Literature Review of Middle‐Aged and Elderly Cases
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DOI: 10.1111/neup.70022
Abstract: Diffuse hemispheric glioma, H3 G34‐mutant (DHG), is a newly defined pediatric‐type tumor in the 2021 WHO classification of central nervous system (CNS) tumors. DHGs harbor missense mutations at codon 35 of H3F3A (H3.3 G35R/V mutations)… read more here.
Keywords: aged elderly; glioma g34; hemispheric glioma; middle aged ... See more keywords
Unraveling the immunologic vulnerabilities of diffuse hemispheric glioma, H3 G34-mutant.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2024.42.16_suppl.2082
Abstract: 2082 Background: Recent insights into the molecular basis of diffuse hemispheric glioma, H3 G34-mutant (DHG-G34), an incurable high-grade glioma, have opened new therapeutic possibilities. The oncohistone mutation in DHG-G34 impairs the epigenetic regulator SETD2, which… read more here.
Keywords: g34; diffuse hemispheric; hemispheric glioma; dhg g34 ... See more keywords