Importance of the Cys124-Cys128 intermolecular disulfide bonding for oligomeric assembly and hemolytic activity of the Helicobacter pylori TlyA hemolysin.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.04.096
Abstract: Although the TlyA hemolysin from Helicobacter pylori has been implicated as a potential virulence factor involved in mediating host cell colonization and hence disease progression, its structural determinants underlying the biological activity are still largely… read more here.
Keywords: disulfide bonding; oligomeric assembly; hemolytic activity; tlya ... See more keywords
Lapatinib Acts against Biofilm Formation and the Hemolytic Activity of Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c00174
Abstract: Biofilm formation and hemolytic activity are closely related to the pathogenesis of Staphylococcus aureus infections. Herein, we show that lapatinib (12.5 μM) significantly inhibits biofilm formation and hemolytic activity of both methicillin-sensitive S. aureus (MSSA)… read more here.
Keywords: hemolytic activity; formation hemolytic; biofilm formation; aureus ... See more keywords
Type VI secretion system-associated FHA domain protein TagH regulates the hemolytic activity and virulence of Vibrio cholerae
Sign Up to like & getrecommendations! Published in 2022 at "Gut Microbes"
DOI: 10.1080/19490976.2022.2055440
Abstract: ABSTRACT The type VI secretion system (T6SS) and hemolysin HlyA are important virulence factors in Vibrio cholerae. The forkhead-associated (FHA) domain is a conserved phosphopeptide binding domain that exists in many regulatory modules. The FHA… read more here.
Keywords: domain protein; hemolytic activity; fha domain; secretion ... See more keywords
HemoNet: Predicting hemolytic activity of peptides with integrated feature learning.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of bioinformatics and computational biology"
DOI: 10.1142/s0219720021500219
Abstract: Quantifying the hemolytic activity of peptides is a crucial step in the discovery of novel therapeutic peptides. Computational methods are attractive in this domain due to their ability to guide wet-lab experimental discovery or screening… read more here.
Keywords: activity peptides; activity; predicting hemolytic; hemonet predicting ... See more keywords
Importance of Propionibacterium acnes hemolytic activity in human intervertebral discs: A microbiological study
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0208144
Abstract: Most patients with chronic lower back pain (CLBP) exhibit degenerative disc disease. Disc specimens obtained during initial therapeutic discectomies are often infected/colonized with Propionibacterium acnes, a Gram-positive commensal of the human skin. Although pain associated… read more here.
Keywords: propionibacterium acnes; hemolytic activity; acnes hemolytic; importance propionibacterium ... See more keywords
Brevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.693725
Abstract: Bacterial non-ribosomally produced peptides (NRPs) form a rich source of antibiotics, including more than 20 of these antibiotics that are used in the clinic, such as penicillin G, colistin, vancomycin, and chloramphenicol. Here we report… read more here.
Keywords: brevibacillin; novel antimicrobial; brevibacillin novel; hemolytic activity ... See more keywords
Hemolytic Activity, Cytotoxicity, and Antimicrobial Effects of Silver Nanoparticles Conjugated with Lincomycin or Cefazolin
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213709
Abstract: The overuse of antibiotics has led to the emergence of resistant bacteria. A good alternative is silver nanoparticles, which have antibacterial activity against Gram-negative and Gram-positive bacteria, including multidrug-resistant strains. Their combination with already known… read more here.
Keywords: activity cytotoxicity; hemolytic activity; silver nanoparticles; activity ... See more keywords
Hemolytic Activity in Relation to the Photosynthetic System in Chattonella marina and Chattonella ovata
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DOI: 10.3390/md19060336
Abstract: Chattonella species, C. marina and C. ovata, are harmful raphidophycean flagellates known to have hemolytic effects on many marine organisms and resulting in massive ecological damage worldwide. However, knowledge of the toxigenic mechanism of these… read more here.
Keywords: hemolytic activity; chattonella; system; marina ovata ... See more keywords
Evaluating the Antimicrobial and Anti-Hemolytic Activity of Synthesized Pseudopeptide against Leptospiral Species: In Silico and In Vitro Approach
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031106
Abstract: Bacterial infections are one of the leading causes of morbidity, mortality, and healthcare complications in patients. Leptospirosis is found to be the most prevalent, re-emergent, and neglected tropical zoonotic disease worldwide. The adaptation to various… read more here.
Keywords: evaluating antimicrobial; activity synthesized; antimicrobial anti; anti hemolytic ... See more keywords
Particles Morphology Impact on Cytotoxicity, Hemolytic Activity and Sorption Properties of Porous Aluminosilicates of Kaolinite Group
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12152559
Abstract: A comparative study of the properties of aluminosilicates of the kaolinite (Al2Si2O5(OH)4∙nH2O) group with different particles morphology has been carried out. Under conditions of directed hydrothermal synthesis, kaolinite nanoparticles with spherical, sponge, and platy morphologies… read more here.
Keywords: sorption; aluminosilicates kaolinite; hemolytic activity; particles morphology ... See more keywords
Hemolytic Activity and Cytotoxicity of Synthetic Nanoclays with Montmorillonite Structure for Medical Applications
Sign Up to like & getrecommendations! Published in 2023 at "Nanomaterials"
DOI: 10.3390/nano13091470
Abstract: The factors influencing the appearance of toxicity in samples of synthetic montmorillonite with a systematically changing chemical composition Nax(Al, Mg)2-3Si4O10(OH)2 nH2O, which are potentially important for their use in medicine as drug carriers, targeted drug… read more here.
Keywords: activity cytotoxicity; synthetic nanoclays; cytotoxicity synthetic; hemolytic activity ... See more keywords