Screening tools for hereditary hemolytic anemia: new concepts and strategies
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Hematology"
DOI: 10.1080/17474086.2021.1886919
Abstract: Abstract Introduction Hereditary hemolytic anemias are a group of rare and heterogeneous disorders due to abnormalities in structure, metabolism, and transport functions of erythrocytes; they may overlap in clinical and hematological features making differential diagnosis… read more here.
Keywords: tools hereditary; hemolytic anemias; screening tools; hemolytic anemia ... See more keywords
New Insights into Hemolytic Anemias: Ultrastructural and Nanomechanical Investigation of Red Blood Cells Showed Early Morphological Changes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomedical nanotechnology"
DOI: 10.1166/jbn.2022.3267
Abstract: Several diseases are characterized by changes in the mechanical properties of erythrocytes. Hemolytic anemias are an example of these diseases. Among the hemolytic anemias, Sickle Cell Disease and Thalassemia are the most common, characterized by… read more here.
Keywords: hemolytic anemias; thalassemia; early morphological; blood ... See more keywords
A Unique Monocyte Transcriptome Discriminates Sickle Cell Disease from Other Hereditary Hemolytic Anemias and Shows the Particular Importance of Lipid and Interferon Signaling
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-124070
Abstract: Introduction Sickle cell disease (SCD) is a hereditary hemolytic disease characterized by a complex pathophysiology including inflammation and oxidative stress. Intravascular hemolysis leads to release of heme, an erythrocyte-derived Danger Associated Molecular Pattern (e-DAMP) that… read more here.
Keywords: hemolytic anemias; healthy controls; disease; scd ... See more keywords
Erythropoietin Is Associated with a Decline in the iFGF23/cFGF23 Ratio in Patients with Various Hereditary Hemolytic Anemias
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-124074
Abstract: Background Recently, erythropoietin (EPO) was identified as an important regulator of production and cleavage of fibroblast growth factor 23 (FGF23). Since erythroid progenitor cells express high levels of FGF23 and carry the FGF receptor, they… read more here.
Keywords: fgf23; research; hemolytic anemias; cfgf23 ... See more keywords
Use of Next Generation Sequencing Panel to Clarify Undiagnosed Cases of Hereditary Hemolytic Anemias
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DOI: 10.1182/blood.v130.suppl_1.3480.3480
Abstract: Background. Hereditary chronic hemolytic anemias (CHAs) is an heterogeneous group of rare disorders including defects of the RBC membrane (hereditary spherocytosis (HS), elliptocytosis (HE), pyropoikilocytosis (HPP), or defects of cation permeability, hereditary stomatocytosis (HSt)), defects… read more here.
Keywords: diagnosis; hemolytic anemias; case; panel ... See more keywords