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Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27859
Abstract: Gene therapy using an adeno‐associated virus (AAV) vector offers a new treatment option for individuals with monogenetic disorders. The major bottleneck is the presence of pre‐existing anti‐AAV antibodies, which impacts its use. Even very low…
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Keywords:
hemophilia patients;
associated virus;
adeno associated;
age ... See more keywords
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Published in 2018 at "Journal of Religion and Health"
DOI: 10.1007/s10943-018-0621-3
Abstract: Spirituality plays an important role in coping with chronic diseases. However, the meaning of spirituality is not known in hemophilia, as a chronic disease. This study aimed to explore the essence of spirituality in hemophilia…
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Keywords:
god;
spirituality experiences;
study;
spirituality ... See more keywords
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Published in 2022 at "International Journal of Hematology"
DOI: 10.1007/s12185-021-03276-7
Abstract: Emicizumab reduces bleeding events in patients with severe hemophilia A (HA). The coagulation potential of emicizumab at a clinical dose appears to correspond to about 15 IU/dL of factor VIII activity (FVIII:C), the equivalent of…
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Keywords:
coagulation potential;
hemophilia patients;
emi pwha;
bleeding ... See more keywords
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Published in 2019 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2019.101598
Abstract: Hemophilia (HP), the deficiency of clotting factors such as VIII (FVIII) and IX, is an inherited blood disorder which is due to the lack of clotting protein. Conventional techniques for detecting hemophilia are based on…
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Keywords:
detection;
detection hemophilia;
hemophilia patients;
spectroscopy ... See more keywords
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Published in 2022 at "Thrombosis and Haemostasis"
DOI: 10.1055/a-2071-0477
Abstract: To identify recurrent inflammation in hemophilia, we assessed the acute-phase response in the blood of patients with hemophilia A and B. Compared to age- and weight-matched controls, blood levels of interleukin-6 (IL-6), C-reactive protein (CRP)…
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Keywords:
phase response;
hemophilia patients;
acute phase;
hemophilia ... See more keywords
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Published in 2020 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0040-1710591
Abstract: BACKGROUND von Willebrand factor (VWF) is crucial for optimal dosing of factor VIII (FVIII) concentrate in hemophilia A patients as it protects FVIII from premature clearance. To date, it is unknown how VWF behaves and…
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Keywords:
vwf gpibm;
hemophilia patients;
vwf vwf;
clearance ... See more keywords
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Published in 2021 at "Hematology"
DOI: 10.1080/16078454.2021.1885123
Abstract: OBJECTIVE This study aimed to compare the cost-effectiveness of these two regimens in hemophilia A patients, under-12-years-old in southern Iran. METHODS A cost-effectiveness study comparing prophylaxis versus on-demand was conducted on 34 hemophilia patients (24…
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Keywords:
cost;
hemophilia patients;
cost effectiveness;
patients years ... See more keywords
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Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029667
Abstract: Total hip arthroplasty (THA) has been an effective tool of advanced hemophiliac hip arthritis. There are only limited data of bilateral synchronous THA for end-stage arthropathy in hemophilia A patients. The aim of this retrospective…
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Keywords:
end stage;
hemophilia patients;
hip;
stage arthropathy ... See more keywords
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Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033298
Abstract: To analyze existing literature and understand how to balance the minimization of bleeding risk and ensuring adequate anticoagulation during coronary intervention treatment and long-term postoperative anticoagulation in hemophilia patients during the perioperative period, in order…
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Keywords:
coronary syndrome;
hemophilia patients;
acute coronary;
management ... See more keywords
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Published in 2020 at "Blood"
DOI: 10.1182/blood-2020-139241
Abstract: Objective:Investigation the survival status of patients with hemophilia in Guangdong during the COVID-19 pandemic, and exploring the effectiveness of coping strategies to provide some experience and inspiration for the management of rare chronic diseases such…
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Keywords:
years old;
treatment;
hemophilia patients;
hemophilia ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1019275
Abstract: The development of coagulation factor VIII (FVIII) inhibitory antibodies is a serious complication in hemophilia A (HA) patients after FVIII replacement therapy. Inhibitors render regular prophylaxis ineffective and increase the risk of morbidity and mortality.…
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Keywords:
hemophilia patients;
inhibitors mechanistic;
novel therapeutic;
insights novel ... See more keywords