Serological biomarkers in hemophilic arthropathy: Can they be used to monitor bleeding and ongoing progression of blood-induced joint disease in patients with hemophilia?
Sign Up to like & getrecommendations! Published in 2019 at "Blood reviews"
DOI: 10.1016/j.blre.2019.100642
Abstract: In patients with hemophilia, levels of uCTX-II and sCS846 increase 5Â days after joint hemorrhage with respect to the initial value. In other words, in patients with established hemophilic arthropathy, the aforesaid biomarkers of joint tissue… read more here.
Keywords: patients hemophilia; biomarkers hemophilic; arthropathy used; blood ... See more keywords
Long-term clinical outcomes following total knee arthroplasty in patients with hemophilic arthropathy: a single-surgeon cohort after a 10- to 17-year follow-up.
Sign Up to like & getrecommendations! Published in 2023 at "Chinese medical journal"
DOI: 10.1097/cm9.0000000000002677
Abstract: BACKGROUND Total knee arthroplasty (TKA) can reduce severe joint pain and improve functional disability in hemophilia. However, the long-term outcomes have rarely been reported in China. Therefore, this study aimed to evaluate the long-term outcomes… read more here.
Keywords: long term; year; knee arthroplasty; hemophilic arthropathy ... See more keywords
What is the Effect of Bevacizumab on Cartilage and Synovium in a Rabbit Model of Hemophilic Arthropathy?
Sign Up to like & getrecommendations! Published in 2023 at "Clinical orthopaedics and related research"
DOI: 10.1097/corr.0000000000002628
Abstract: BACKGROUND Hemophilic arthropathy can cause recurrent hemarthroses and severe damage to the synovium and articular cartilage. Previous studies have shown that vascular endothelial growth factor (VEGF) plays an essential role in neoangiogenesis. Bevacizumab, a monoclonal… read more here.
Keywords: cartilage; intra articular; severe arthropathy; group ... See more keywords
The potential role of protease systems in hemophilic arthropathy
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2022007028
Abstract: Abstract Hemophilic arthropathy (HA) is characterized by joint damage following recurrent joint bleeds frequently observed in patients affected by the clotting disorder hemophilia. Joint bleeds or hemarthroses trigger inflammation in the synovial tissue, which promotes… read more here.
Keywords: joint damage; protease; role; cartilage ... See more keywords
Shared Decision-Making in Hemophilic Arthropathy Rehabilitation: A Qualitative Study
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DOI: 10.2147/ppa.s394095
Abstract: Purpose To probe into the needs and barriers underlying patients’ participation in shared decision-making related to rehabilitation nursing for hemophilic arthropathy. Patients and Methods The phenomenological research approach was adopted to conduct a series of… read more here.
Keywords: rehabilitation; decision making; hemophilic arthropathy; decision ... See more keywords
Pathophysiological Role of Synovitis in Hemophilic Arthropathy Development: A Two-Hit Hypothesis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00541
Abstract: Despite an increasing access to prophylaxis with clotting factor concentrates, arthropathy still represents the main chronic complication of hemophilia. Whereas previous studies described hemophilic arthropathy (HA) as a degenerative arthropathy, somehow resembling osteoarthritis (OA), most… read more here.
Keywords: hit; role synovitis; hemophilic arthropathy; pathophysiological role ... See more keywords
The Application of Focused Medium-Energy Extracorporeal Shockwave Therapy in Hemophilic A Arthropathy
Sign Up to like & getrecommendations! Published in 2022 at "Healthcare"
DOI: 10.3390/healthcare10020352
Abstract: Hemophilic arthropathy causes the damage of synovium, cartilage, and subchondral bone. The present study evaluated the safety and the effect of extracorporeal shockwave therapy (ESWT), a safe treatment widely used in musculoskeletal conditions in patients… read more here.
Keywords: extracorporeal shockwave; shockwave therapy; hemophilic arthropathy; medium energy ... See more keywords