Effect of Low-Dose Supplementation of Arginine Vasopressin on Need for Blood Product Transfusions in Patients With Trauma and Hemorrhagic Shock: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA surgery"
DOI: 10.1001/jamasurg.2019.2884
Abstract: Importance Current therapies for traumatic blood loss focus on hemorrhage control and blood volume replacement. Severe hemorrhagic shock, however, is associated with a state of arginine vasopressin (AVP) deficiency, and supplementation of this hormone may… read more here.
Keywords: low dose; blood product; blood; hemorrhagic shock ... See more keywords
Low‐Fouling Zwitterionic Polymeric Colloids as Resuscitation Fluids for Hemorrhagic Shock
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DOI: 10.1002/adma.202207376
Abstract: Colloids, known as volume expanders, have been used as resuscitation fluids for hypovolemic shock for decades, as they increase plasma oncotic pressure and expand intravascular volume. However, recent studies show that commonly used synthetic colloids… read more here.
Keywords: resuscitation fluids; hemorrhagic shock; low fouling; volume ... See more keywords
Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats
Sign Up to like & getrecommendations! Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1501
Abstract: Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis. Mitochondrial permeability transition pore (mPTP) plays an important role in apoptosis, but it is unknown… read more here.
Keywords: sevoflurane postconditioning; hemorrhagic shock; mitochondrial permeability; transition pore ... See more keywords
Hemorrhagic Shock and the Microvasculature.
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DOI: 10.1002/cphy.c170006
Abstract: The microvasculature plays a central role in the pathophysiology of hemorrhagic shock and is also involved in arguably all therapeutic attempts to reverse or minimize the adverse consequences of shock. Microvascular studies specific to hemorrhagic… read more here.
Keywords: shock microvasculature; physiology; hemorrhagic shock; shock ... See more keywords
Resuscitation Fluid with Drag Reducing Polymer Enhances Cerebral Microcirculation and Tissue Oxygenation After Traumatic Brain Injury Complicated by Hemorrhagic Shock.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-91287-5_7
Abstract: Traumatic brain injury (TBI) is frequently accompanied by hemorrhagic shock (HS) which significantly worsens morbidity and mortality. Existing resuscitation fluids (RF) for volume expansion inadequately mitigate impaired microvascular cerebral blood flow (mvCBF) and hypoxia after… read more here.
Keywords: traumatic brain; hemorrhagic shock; tissue; resuscitation ... See more keywords
Effects of crystalloids and colloids on microcirculation, central venous oxygen saturation, and central venous-to-arterial carbon dioxide gap in a rabbit model of hemorrhagic shock
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2594-5
Abstract: ObjectiveThe effects of hydroxyethyl starch (HES) on microcirculation, central venous oxygen saturation (ScvO2), and the central venous-to-arterial carbon dioxide gap (dCO2) are studied in a rabbit model of hemorrhagic shock for elucidating the advantages and… read more here.
Keywords: microcirculation; group; central venous; hemorrhagic shock ... See more keywords
CORR Insights®: Severe Hemorrhagic Shock Leads to a Delayed Fracture Healing and Decreased Bone Callus Strength in a Mouse Model
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Orthopaedics and Related Research"
DOI: 10.1007/s11999.0000000000000151
Abstract: Previously published experimental studies have shown contradictory results regarding hemorrhagic shock and its impact on fracture healing. Some suggest that trauma hemorrhage leads to increased osteocyte necrosis and delayed fracture healing [10, 12], whereas others… read more here.
Keywords: fracture healing; bone; model; hemorrhagic shock ... See more keywords
Carboxyfullerene nanoparticles alleviate acute hepatic injury in severe hemorrhagic shock.
Sign Up to like & getrecommendations! Published in 2017 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2016.10.022
Abstract: Hemorrhagic shock/resuscitation involves overwhelming reactive oxygen species (ROS) that cause oxidative stress, inflammation, and subsequent tissue injury. We investigated the effects of the potent antioxidant carboxyfullerene (C3) on acute liver injury during hemorrhage shock/resuscitation. C3… read more here.
Keywords: injury; shock resuscitation; hemorrhagic shock; shock ... See more keywords
[Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats].
Sign Up to like & getrecommendations! Published in 2019 at "Revista brasileira de anestesiologia"
DOI: 10.1016/j.bjan.2018.09.011
Abstract: BACKGROUND AND OBJECTIVES Dexmedetomidine has demonstrated protective effects against lung injury in vitro. Here, we investigated whether dexmedetomidine preconditioning protected against lung injury in hemorrhagic shock rats. METHODS Male Sprague-Dawley rats were randomly divided into… read more here.
Keywords: dexmedetomidine; dexmedetomidine preconditioning; lung injury; hemorrhagic shock ... See more keywords
REFRACTORY HEMORRHAGIC SHOCK SECONDARY TO ACQUIRED HEMOPHILIA A
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DOI: 10.1016/j.chest.2019.08.1948
Abstract: A week later, she was re-admitted with a syncopal episode. Her hemoglobin was 6.1 g/dL. Computed tomography (CT) showed retroperitoneal (RP) bleeding. She was transferred to our tertiary hospital and was found to be in… read more here.
Keywords: acquired hemophilia; shock secondary; secondary acquired; hemorrhagic shock ... See more keywords
Comparison of the effects of volemic reposition with 7.5% NaCl or blood in an experimental model of muscular compression and hemorrhagic shock☆
Sign Up to like & getrecommendations! Published in 2018 at "Revista Brasileira de Ortopedia"
DOI: 10.1016/j.rboe.2018.07.006
Abstract: Objective Crush syndrome is characterized by traumatic muscular injuries with severe systemic clinical repercussions. The systemic inflammatory reaction characterized acutely by infiltration of neutrophils in the lungs has been studied as part of the spectrum… read more here.
Keywords: crush syndrome; compression; hemorrhagic shock; model ... See more keywords