Collateral and permeability imaging derived from dynamic contrast material-enhanced MR angiography in prediction of PH 2 hemorrhagic transformation after acute ischemic stroke: a pilot study
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DOI: 10.1007/s00234-021-02655-5
Abstract: To evaluate the role of collateral and permeability imaging derived from dynamic contrast material-enhanced magnetic resonance angiography to predict PH 2 hemorrhagic transformation in acute ischemic stroke. The secondary analysis of a published data from… read more here.
Keywords: transformation; permeability imaging; dynamic contrast; contrast material ... See more keywords
Blood-brain barrier permeability assessed by perfusion computed tomography predicts hemorrhagic transformation in acute reperfusion therapy
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DOI: 10.1007/s10072-018-3468-1
Abstract: Hemorrhagic transformation (HT) is one of the most feared complications of acute recanalization therapies. The aim of this study was to evaluate whether blood-brain barrier permeability (BBBP) imaging can predict HT in the setting of… read more here.
Keywords: blood brain; bbbp; barrier permeability; brain barrier ... See more keywords
Lymphocyte-to-monocyte ratio and risk of hemorrhagic transformation in patients with acute ischemic stroke
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DOI: 10.1007/s10072-020-04355-z
Abstract: Background Hemorrhagic transformation (HT) is a common complication of acute ischemic stroke (AIS), and inflammation has been found to play an important role in the occurrence of HT. We aimed to investigate the impact of… read more here.
Keywords: lymphocyte monocyte; ischemic stroke; acute ischemic; lmr ... See more keywords
Early Increased Bradykinin 1 Receptor Contributes to Hemorrhagic Transformation After Ischemic Stroke in Type 1 Diabetic Rats
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DOI: 10.1007/s12975-017-0552-4
Abstract: Hemorrhagic transformation (HT) is a major complication of ischemic stroke and further deteriorates neurological outcomes. Bradykinin 1 receptor (B1R) has been proven to mediate vasculo-toxicity in various experimental models. However, its role in the development… read more here.
Keywords: ischemic stroke; bradykinin receptor; type; b1r ... See more keywords
Glycyrrhizin Prevents Hemorrhagic Transformation and Improves Neurological Outcome in Ischemic Stroke with Delayed Thrombolysis Through Targeting Peroxynitrite-Mediated HMGB1 Signaling
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DOI: 10.1007/s12975-019-00772-1
Abstract: Peroxynitrite (ONOO−) and high mobility group box 1 protein (HMGB1) are important cytotoxic factors contributing to cerebral ischemia-reperfusion injury. However, the roles of ONOO− in mediating HMGB1 expression and its impacts on hemorrhagic transformation (HT)… read more here.
Keywords: hmgb1; hemorrhagic transformation; ischemic stroke; delayed treatment ... See more keywords
YiQiFuMai Lyophilized Injection ameliorates tPA-Induced hemorrhagic transformation by inhibiting cytoskeletal rearrangement associated with ROCK1 and NF-κB signaling pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2020.113161
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Thrombolytic therapy with tissue plasminogen activator (tPA) after ischemic stroke exacerbates blood-brain barrier (BBB) breakdown and leads to hemorrhagic transformation (HT). YiQiFuMai Lyophilized Injection (YQFM) is a modern preparation derived from Sheng-mai San,… read more here.
Keywords: yqfm; tpa; yiqifumai lyophilized; tpa induced ... See more keywords
Serum homocysteine level is an independent predictor for hemorrhagic transformation within 24 h of intravenous thrombolysis in acute ischemic stroke
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2020.10.021
Abstract: The study aimed to investigate the role of serum homocysteine in hemorrhagic transformation (HT) and symptomatic intracranial hemorrhage (sICH) within 24 h of intravenous (IV) recombinanttissueplasminogenactivator(rt-PA) in acute ischemic stroke (AIS) patients. 236 consecutive AIS patients… read more here.
Keywords: serum homocysteine; within intravenous; serum; homocysteine level ... See more keywords
Safety and Outcomes of Intravenous Thrombolytic Therapy in Ischemic Stroke Patients with COVID-19: CASCADE Initiative
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DOI: 10.1016/j.jstrokecerebrovasdis.2021.106121
Abstract: Background There is little information regarding the safety of intravenous tissue plasminogen activator (IV-tPA) in patients with stroke and COVID-19. Methods This multicenter study included consecutive stroke patients with and without COVID-19 treated with IV-tPA… read more here.
Keywords: covid; patients covid; stroke patients; hemorrhagic transformation ... See more keywords
Role of anticoagulant therapy in hemorrhagic transformation of acute ischaemic stroke in patients with non‐valvular atrial fibrillation: reply to commentaries
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DOI: 10.1111/ene.13827
Abstract: We would like to thank George Vilanilam and colleagues for their interest in our article [1]. As they correctly state, it is plausible that treatment with intravenous thrombolysis (IVT) could have influenced the association between… read more here.
Keywords: patients treated; treatment; association; ischaemic stroke ... See more keywords
Serum Albumin Is Negatively Associated with Hemorrhagic Transformation in Acute Ischemic Stroke Patients
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DOI: 10.1159/000498855
Abstract: Background and Objective: Hemorrhagic transformation (HT) is a major complication of acute ischemic stroke (AIS). Serum albumin is known for its neuroprotective effects and is a marker of improved AIS patient outcomes. However, it is… read more here.
Keywords: ischemic stroke; serum; acute ischemic; hemorrhagic transformation ... See more keywords
Correlation Between Computed Tomography-Based Tissue Net Water Uptake and Volumetric Measures of Cerebral Edema After Reperfusion Therapy.
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DOI: 10.1161/strokeaha.121.037073
Abstract: BACKGROUND Cerebral edema after large hemispheric infarction is associated with poor functional outcome and mortality. Net water uptake (NWU) quantifies the degree of hypoattenuation on unenhanced-computed tomography (CT) and is increasingly used to measure cerebral… read more here.
Keywords: hemorrhagic transformation; nwu; thrombectomy; cerebral edema ... See more keywords