Articles with "hemostatic effect" as a keyword



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Biodegradable hydrogel with thermo-response and hemostatic effect for photothermal enhanced anti-infective therapy

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Published in 2021 at "Nano Today"

DOI: 10.1016/j.nantod.2021.101165

Abstract: Abstract Massive bleeding and infectious complication remain the leading cause of worldwide trauma deaths. To tackle this issue, a platelet-inspired degradable antibacterial hydrogel (Gel/PP-TA-Ag) is synthesized based on gelatin methacrylate (GelMA), tannic acid (TA), polyphosphate… read more here.

Keywords: biodegradable hydrogel; photothermal; hemostatic effect; hydrogel thermo ... See more keywords
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Hemostatic Effect of 20(S)-Panaxadiol by Induced Platelet Aggregation Depending on Calcium Signaling Pathway

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Published in 2022 at "BioMed Research International"

DOI: 10.1155/2022/8265898

Abstract: Panax notoginseng (Burk.) F.H. Chen is the most traditional hemostatic herb in China. Our previous research found that 20(S)-protopanaxadiol showed the hemostatic effect. And 20(S)-panaxadiol (PD) has a similar structure to 20(S)-protopanaxadiol with a dammarane… read more here.

Keywords: calcium; hemostatic effect; effect panaxadiol; platelet aggregation ... See more keywords
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Hemostatic effect and safety evaluation of the absorbable macroporous polysaccharides composite hemostatic material prepared by a green fabrication approach

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Published in 2022 at "Journal of Biomaterials Applications"

DOI: 10.1177/08853282221139026

Abstract: Carboxymethyl chitosan is widely used in the medical field such as wound healing and other medical fields. We previously fabricated the absorbable macroporous polysaccharides composite hemostatics (AMPCs) mainly composed of carboxymethyl chitosan which possess excellent… read more here.

Keywords: absorbable macroporous; macroporous polysaccharides; effect; polysaccharides composite ... See more keywords

Factor VIIa induces extracellular vesicles from the endothelium: A potential mechanism for its hemostatic effect.

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Published in 2021 at "Blood"

DOI: 10.1182/blood.2020008417

Abstract: Recombinant FVIIa (rFVIIa) is used as a hemostatic agent to treat bleeding disorders in hemophilia patients with inhibitors and other groups of patients. Our recent studies showed that FVIIa binds endothelial cell protein C receptor… read more here.

Keywords: extracellular vesicles; fviia; par1; epcr ... See more keywords
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Factor VIIa interaction with EPCR modulates the hemostatic effect of rFVIIa in hemophilia therapy: Mode of its action.

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Published in 2017 at "Blood advances"

DOI: 10.1182/bloodadvances.2016004143

Abstract: Recent studies established that clotting factor VIIa (FVIIa) binds endothelial cell protein C receptor (EPCR). It has been speculated that FVIIa interaction with EPCR might augment the hemostatic effect of rFVIIa in therapeutic conditions. The… read more here.

Keywords: epcr; hemostatic effect; effect rfviia; interaction epcr ... See more keywords