Effects of platelet-sparing leukocyte reduction and agitation methods on in vitro measures of hemostatic function in cold-stored whole blood
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000001870
Abstract: BACKGROUND Agitation of platelet units stored at room temperature is performed routinely to maintain platelet function, and leukoreduction of blood products is the standard of care in many countries to reduce immune consequences of transfusion.… read more here.
Keywords: agitation; hemostatic function; whole blood; blood ... See more keywords
Hemostatic function in Cavalier King Charles Spaniels assessed using thromboelastography.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary clinical pathology"
DOI: 10.1111/vcp.12795
Abstract: BACKGROUND Macrothrombocytopenia is a well-known anomaly in Cavalier King Charles Spaniels (CKCSs), a breed also highly predisposed to develop myxomatous mitral valve disease (MMVD). Thromboelastography (TEG) has been shown to be a valuable instrument for… read more here.
Keywords: charles spaniels; king charles; teg; hemostatic function ... See more keywords
Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24087386
Abstract: Implantable Cardiovascular Therapeutic Devices (CTD), while lifesaving, impart supraphysiologic shear stress to platelets, resulting in thrombotic and bleeding coagulopathy. We previously demonstrated that shear-mediated platelet dysfunction is associated with downregulation of platelet GPIb-IX-V and αIIbβ3… read more here.
Keywords: hemostatic function; morphology; shear mediated; heterogeneity morphology ... See more keywords