Articles with "hendra virus" as a keyword



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Hendra virus: Epidemiology dynamics in relation to climate change, diagnostic tests and control measures

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Published in 2020 at "One Health"

DOI: 10.1016/j.onehlt.2020.100207

Abstract: Hendra virus (HeV) continues to pose a serious public health concern as spillover events occur sporadically. Terminally ill horses can exhibit a range of clinical signs including frothy nasal discharge, ataxia or forebrain signs. Early… read more here.

Keywords: hendra virus; diagnostic tests; epidemiology; climate change ... See more keywords
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Circulating microRNA profiles of Hendra virus infection in horses

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Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-06939-w

Abstract: Hendra virus (HeV) is an emerging zoonotic pathogen harbored by Australian mainland flying foxes. HeV infection can cause lethal disease in humans and horses, and to date all cases of human HeV disease have resulted… read more here.

Keywords: hendra virus; infection; circulating microrna; hev ... See more keywords
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Potent monoclonal antibody–mediated neutralization of a divergent Hendra virus variant

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2122769119

Abstract: Significance A new Hendra virus variant (HeV-g2) has been recently identified in two independent studies, increasing the concern of HeV spillover. Here, we show that HeV-g2 utilizes the same host receptor as HeV and that… read more here.

Keywords: hendra virus; monoclonal antibody; hev; virus variant ... See more keywords
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Mutations in the Transmembrane Domain and Cytoplasmic Tail of Hendra Virus Fusion Protein Disrupt Virus-Like-Particle Assembly

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Published in 2017 at "Journal of Virology"

DOI: 10.1128/jvi.00152-17

Abstract: ABSTRACT Hendra virus (HeV) is a zoonotic paramyxovirus that causes deadly illness in horses and humans. An intriguing feature of HeV is the utilization of endosomal protease for activation of the viral fusion protein (F).… read more here.

Keywords: hendra virus; fusion protein; virus;
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A network approach for provisional assay recognition of a Hendra virus antibody ELISA: test validation with low sample numbers from infected horses

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Published in 2018 at "Journal of Veterinary Diagnostic Investigation"

DOI: 10.1177/1040638718760102

Abstract: Obtaining statistically sound numbers of sera from Hendra virus (HeV)-infected horses is problematic because affected individuals usually die or are euthanized before developing a serum antibody response. As a consequence, test validation becomes a challenge.… read more here.

Keywords: test validation; validation; antibody; hendra virus ... See more keywords
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A new Hendra virus genotype found in Australian flying foxes

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Published in 2021 at "Virology Journal"

DOI: 10.1186/s12985-021-01652-7

Abstract: Background Hendra virus (HeV) has caused lethal disease outbreaks in humans and horses in Australia. Flying foxes are the wildlife reservoir from which the virus was first isolated in 1996. Following a heat stress mortality… read more here.

Keywords: flying foxes; hendra virus; genotype; hev ... See more keywords
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Novel Hendra Virus Variant Circulating in Black Flying Foxes and Grey-Headed Flying Foxes, Australia

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Published in 2022 at "Emerging Infectious Diseases"

DOI: 10.3201/eid2805.212338

Abstract: A novel Hendra virus variant, genotype 2, was recently discovered in a horse that died after acute illness and in Pteropus flying fox tissues in Australia. We detected the variant in flying fox urine, the… read more here.

Keywords: hendra virus; flying foxes; virus variant; novel hendra ... See more keywords
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Development and laboratory evaluation of a competitive ELISA for serodiagnosis of Nipah and Hendra virus infection using recombinant Nipah glycoproteins and a monoclonal antibody

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Published in 2023 at "Frontiers in Veterinary Science"

DOI: 10.3389/fvets.2023.1120367

Abstract: Introduction Nipah virus (NiV) and Hendra virus (HeV), of the genus Henipavirus, family Paramyxoviridae, are classified as Risk Group 4 (RG4) pathogens that cause respiratory disease in pigs and acute/febrile encephalitis in humans with high… read more here.

Keywords: monoclonal antibody; hendra virus; virus; celisa ... See more keywords
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Discovery of Potential Antiviral Compounds against Hendra Virus by Targeting Its Receptor-Binding Protein (G) Using Computational Approaches

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27020554

Abstract: Hendra virus (HeV) belongs to the paramyxoviridae family of viruses which is associated with the respiratory distress, neurological illness, and potential fatality of the affected individuals. So far, no competitive approved therapeutic substance is available… read more here.

Keywords: discovery potential; antiviral compounds; hendra virus; receptor ... See more keywords
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Communication Interventions and Assessment of Drivers for Hendra Virus Vaccination Uptake

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Published in 2023 at "Vaccines"

DOI: 10.3390/vaccines11050936

Abstract: Hendra virus disease (HeVD) is an emerging zoonosis in Australia, resulting from the transmission of Hendra virus (HeV) to horses from Pteropus bats. Vaccine uptake for horses is low despite the high case fatality rate… read more here.

Keywords: communication interventions; vaccine uptake; hev vaccine; hendra virus ... See more keywords
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PHYSIOLOGIC BIOMARKERS AND HENDRA VIRUS INFECTION IN AUSTRALIAN BLACK FLYING FOXES (PTEROPUS ALECTO)

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Published in 2017 at "Journal of Wildlife Diseases"

DOI: 10.7589/2016-05-100

Abstract: Abstract Bats of the genus Pteropus (Pteropodidae), colloquially known as flying foxes, are recognized as the natural reservoir of Hendra virus, a zoonotic paramyxovirus responsible for mortality in horses and humans. Some previous studies have… read more here.

Keywords: virus infection; hendra virus; black flying; flying foxes ... See more keywords