A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery.
Sign Up to like & getrecommendations! Published in 2021 at "Antiviral research"
DOI: 10.1016/j.antiviral.2021.105084
Abstract: Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic, bat-borne paramyxoviruses in the genus Henipavirus that cause severe and often fatal acute respiratory and/or neurologic diseases in humans and livestock. There are currently no… read more here.
Keywords: cedar virus; high throughput; henipavirus; virus ... See more keywords
The Henipavirus V protein is a prevalently unfolded protein with a zinc-finger domain involved in binding to DDB1.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00488e
Abstract: Henipaviruses are severe human pathogens within the Paramyxoviridae family. Beyond the P protein, the Henipavirus P gene also encodes the V protein which shares with P its N-terminal, intrinsically disordered region (PNT) and possesses a… read more here.
Keywords: protein; zinc; binding ddb1; henipavirus proteins ... See more keywords
Discovery and Genomic Characterization of a Novel Henipavirus, Angavokely Virus, from Fruit Bats in Madagascar
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00921-22
Abstract: Henipaviruses include highly pathogenic emerging zoonotic viruses, derived from bat, rodent, and shrew reservoirs. Bat-borne Hendra (HeV) and Nipah (NiV) are the most well-known henipaviruses, for which no effective antivirals or vaccines for humans have… read more here.
Keywords: angavokely virus; bat; henipavirus; fruit bats ... See more keywords
Epitope-Based Peptide Vaccine against Glycoprotein G of Nipah Henipavirus Using Immunoinformatics Approaches
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Immunology Research"
DOI: 10.1155/2020/2567957
Abstract: Background Nipah belongs to the genus Henipavirus and the Paramyxoviridae family. It is an endemic most commonly found at South Asia and has first emerged in Malaysia in 1998. Bats are found to be the… read more here.
Keywords: glycoprotein nipah; vaccine glycoprotein; epitope based; henipavirus ... See more keywords
Experimental Evidence of Intrinsic Disorder and Amyloid Formation by the Henipavirus W Proteins
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020923
Abstract: Henipaviruses are severe human pathogens within the Paramyxoviridae family. Beyond the P protein, the Henipavirus P gene also encodes the V and W proteins which share with P their N-terminal, intrinsically disordered domain (NTD) and… read more here.
Keywords: amyloid; henipavirus; intrinsic disorder; experimental evidence ... See more keywords