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   Articles with "hep" as a keyword



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Combining multi-antigenic immunodot with indirect immunofluorescence on HEp-2 cells improves the diagnosis of systemic sclerosis.

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recommendations! Published in 2021 at "Clinical immunology"

DOI: 10.1016/j.clim.2021.108774

Abstract: Systemic sclerosis (SSc) is associated, in nearly all patients, with autoantibodies (Ab). Accordingly, and in order to identify major (anti-CEN A/B and anti-Topo I) but also minor Abs, the usefulness of combining indirect immunofluorescence (IIF)… read more here.

Keywords: ssc; indirect immunofluorescence; multi antigenic; hep ... See more keywords
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A high-entropy perovskite cathode for solid oxide fuel cells

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recommendations! Published in 2021 at "Journal of Alloys and Compounds"

DOI: 10.1016/j.jallcom.2021.159633

Abstract: Abstract A new concept of high-entropy cathode is reported, which can bring about a definite improvement of electrochemical performance for solid oxide fuel cells (SOFCs). As a proof-of-concept, a new high-entropy perovskite oxide of La0.2Pr0.2Nd0.2Sm0.2Ba0.1Sr0.1Co0.2Fe0.6Ni0.1Cu0.1O3-δ… read more here.

Keywords: entropy perovskite; hep; cathode; solid oxide ... See more keywords
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Brusatol inhibits laryngeal cancer cell proliferation and metastasis via abrogating JAK2/STAT3 signaling mediated epithelial-mesenchymal transition.

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recommendations! Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119907

Abstract: AIMS This study aimed at investigating the role of Brusatol (BR) on human laryngeal squamous carcinoma cell (Hep-2) to study its underlying mechanism through in vitro and in vivo approaches. MATERIALS AND METHOD In the… read more here.

Keywords: jak2 stat3; cell proliferation; hep; study ... See more keywords
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Experiment and numerical investigation on structural response of a FMRC hexagon enclosed platform in waves

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recommendations! Published in 2021 at "Ocean Engineering"

DOI: 10.1016/j.oceaneng.2021.108998

Abstract: Abstract Hexagon Enclosed Platform (HEP) provides life accommodation, ship docking and marine replenishment for many ocean-going vessels in deep ocean. The HEP is composed of six trapezoidal floating modules connected by six rigid connectors and… read more here.

Keywords: enclosed platform; response; structural response; hep ... See more keywords
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Nanoparticle Surface Engineering with Heparosan Polysaccharide Reduces Serum Protein Adsorption and Enhances Cellular Uptake.

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recommendations! Published in 2022 at "Nano letters"

DOI: 10.1021/acs.nanolett.2c00349

Abstract: Nanoparticle modification with poly(ethylene glycol) (PEG) is a widely used surface engineering strategy in nanomedicine. However, since the artificial PEG polymer may adversely impact nanomedicine safety and efficacy, alternative surface modifications are needed. Here, we… read more here.

Keywords: surface engineering; coated nanoparticles; surface; hep ... See more keywords
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Heparin Biofunctionalized Selenium Nanoparticles as Potential Antiangiogenic-Chemotherapeutic Agents for Targeted Doxorubicin Delivery.

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recommendations! Published in 2023 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.3c00219

Abstract: Combining antiangiogenic and chemotherapeutic agents has shown promising clinical benefits in cancer cures when the therapeutic intervention takes into account the tissue and molecular targets. Moreover, the risk of induced drug resistance is minimized when… read more here.

Keywords: dox; chemotherapeutic agents; hep; antiangiogenic chemotherapeutic ... See more keywords
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The Predictive Value of the 4Ts and HEP Score at Recommended Cutoffs in Patients With Mechanical Circulatory Support Devices.

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recommendations! Published in 2022 at "Journal of cardiothoracic and vascular anesthesia"

DOI: 10.1053/j.jvca.2022.02.030

Abstract: OBJECTIVES Despite the increasing utilization of mechanical circulatory support (MCS) devices, the 4Ts and heparin-induced thrombocytopenia (HIT) Expert Probability (HEP) scores have not been validated in patients with suspected HIT requiring MCS. DESIGN A retrospective… read more here.

Keywords: hep score; mechanical circulatory; circulatory support; 4ts hep ... See more keywords
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Human Epithelial Type-2 Cell Image Classification Using an Artificial Neural Network with Hybrid Descriptors

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recommendations! Published in 2020 at "IETE Journal of Research"

DOI: 10.1080/03772063.2018.1474810

Abstract: ABSTRACT Antinuclear antibody (ANA) testing is best performed using the indirect immunofluorescence (IIF) method with human epithelial type-2 (HEp-2) cells as the substrate. IIF is a subjective procedure in which HEp-2 patterns are analyzed manually… read more here.

Keywords: epithelial type; image; hep; human epithelial ... See more keywords
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An automatic immunofluorescence pattern classification framework for HEp-2 image based on supervised learning.

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recommendations! Published in 2023 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbad144

Abstract: Immunofluorescence patterns of anti-nuclear antibodies (ANAs) on human epithelial cell (HEp-2) substrates are important biomarkers for the diagnosis of autoimmune diseases. There are growing clinical requirements for an automatic readout and classification of ANA immunofluorescence… read more here.

Keywords: classification; supervised learning; framework; automatic immunofluorescence ... See more keywords
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Heparosan-coated liposomes for drug delivery

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recommendations! Published in 2017 at "Glycobiology"

DOI: 10.1093/glycob/cwx070

Abstract: Liposomal encapsulation is a useful drug delivery strategy for small molecules, especially chemotherapeutic agents such as doxorubicin. Doxil® is a doxorubicin-containing liposome ("dox-liposome") that passively targets drug to tumors while reducing side effects caused by… read more here.

Keywords: drug delivery; hep; drug; heparosan coated ... See more keywords
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Clinical relevance of HEp-2 indirect immunofluorescent patterns: the International Consensus on ANA patterns (ICAP) perspective

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recommendations! Published in 2019 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2018-214436

Abstract: The indirect immunofluorescence assay (IIFA) on HEp-2 cells is widely used for detection of antinuclear antibodies (ANA). The dichotomous outcome, negative or positive, is integrated in diagnostic and classification criteria for several systemic autoimmune diseases.… read more here.

Keywords: clinical relevance; consensus ana; international consensus; consensus ... See more keywords