Potent cytotoxicity and induction of ROS-mediated genomic instability, mitochondrial dysfunction, and apoptosis by Y2O3 NPs in Hep-G2 hepatic cancer cells
Sign Up to like & getrecommendations! Published in 2025 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-025-04051-9
Abstract: Hepatic cancer, one of the most prevalent and lethal cancers globally, remains a significant health challenge, with limited treatment options underscoring the urgent need for novel, more effective therapies. Yttrium oxide nanoparticles (Y2O3 NPs) have… read more here.
Keywords: y2o3 nps; cancer; hepatic cancer; hep ... See more keywords
Combining multi-antigenic immunodot with indirect immunofluorescence on HEp-2 cells improves the diagnosis of systemic sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108774
Abstract: Systemic sclerosis (SSc) is associated, in nearly all patients, with autoantibodies (Ab). Accordingly, and in order to identify major (anti-CEN A/B and anti-Topo I) but also minor Abs, the usefulness of combining indirect immunofluorescence (IIF)… read more here.
Keywords: ssc; indirect immunofluorescence; multi antigenic; hep ... See more keywords
A high-entropy perovskite cathode for solid oxide fuel cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Alloys and Compounds"
DOI: 10.1016/j.jallcom.2021.159633
Abstract: Abstract A new concept of high-entropy cathode is reported, which can bring about a definite improvement of electrochemical performance for solid oxide fuel cells (SOFCs). As a proof-of-concept, a new high-entropy perovskite oxide of La0.2Pr0.2Nd0.2Sm0.2Ba0.1Sr0.1Co0.2Fe0.6Ni0.1Cu0.1O3-δ… read more here.
Keywords: entropy perovskite; hep; cathode; solid oxide ... See more keywords
Brusatol inhibits laryngeal cancer cell proliferation and metastasis via abrogating JAK2/STAT3 signaling mediated epithelial-mesenchymal transition.
Sign Up to like & getrecommendations! Published in 2021 at "Life sciences"
DOI: 10.1016/j.lfs.2021.119907
Abstract: AIMS This study aimed at investigating the role of Brusatol (BR) on human laryngeal squamous carcinoma cell (Hep-2) to study its underlying mechanism through in vitro and in vivo approaches. MATERIALS AND METHOD In the… read more here.
Keywords: jak2 stat3; cell proliferation; hep; study ... See more keywords
Experiment and numerical investigation on structural response of a FMRC hexagon enclosed platform in waves
Sign Up to like & getrecommendations! Published in 2021 at "Ocean Engineering"
DOI: 10.1016/j.oceaneng.2021.108998
Abstract: Abstract Hexagon Enclosed Platform (HEP) provides life accommodation, ship docking and marine replenishment for many ocean-going vessels in deep ocean. The HEP is composed of six trapezoidal floating modules connected by six rigid connectors and… read more here.
Keywords: enclosed platform; response; structural response; hep ... See more keywords
Nanoparticle Surface Engineering with Heparosan Polysaccharide Reduces Serum Protein Adsorption and Enhances Cellular Uptake.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c00349
Abstract: Nanoparticle modification with poly(ethylene glycol) (PEG) is a widely used surface engineering strategy in nanomedicine. However, since the artificial PEG polymer may adversely impact nanomedicine safety and efficacy, alternative surface modifications are needed. Here, we… read more here.
Keywords: surface engineering; coated nanoparticles; surface; hep ... See more keywords
Heparin Biofunctionalized Selenium Nanoparticles as Potential Antiangiogenic-Chemotherapeutic Agents for Targeted Doxorubicin Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c00219
Abstract: Combining antiangiogenic and chemotherapeutic agents has shown promising clinical benefits in cancer cures when the therapeutic intervention takes into account the tissue and molecular targets. Moreover, the risk of induced drug resistance is minimized when… read more here.
Keywords: dox; chemotherapeutic agents; hep; antiangiogenic chemotherapeutic ... See more keywords
Carbon dots with red emission as nanoprobe for sensing of heparin in biofluids and pharmaceutical samples
Sign Up to like & getrecommendations! Published in 2025 at "RSC Advances"
DOI: 10.1039/d4ra06655c
Abstract: Heparin (HEP) is one of the oldest anticoagulant drugs, widely used in clinical settings, particularly in surgery and dialysis machines. Despite its long history, it remains extensively employed in medical practice. This study introduces a… read more here.
Keywords: red emission; carbon dots; emission nanoprobe; dots red ... See more keywords
The Predictive Value of the 4Ts and HEP Score at Recommended Cutoffs in Patients With Mechanical Circulatory Support Devices.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2022.02.030
Abstract: OBJECTIVES Despite the increasing utilization of mechanical circulatory support (MCS) devices, the 4Ts and heparin-induced thrombocytopenia (HIT) Expert Probability (HEP) scores have not been validated in patients with suspected HIT requiring MCS. DESIGN A retrospective… read more here.
Keywords: hep score; mechanical circulatory; circulatory support; 4ts hep ... See more keywords
Towards eliminating hepatocellular carcinoma from Aotearoa New Zealand: a nationally coordinated programme to detect and treat chronic hepatitis?
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Royal Society of New Zealand"
DOI: 10.1080/03036758.2025.2491511
Abstract: ABSTRACT Hepatocellular carcinoma (HCC) is the seventh most common cancer globally, with 1 million people diagnosed and 830,000 cancer-related deaths annually, demonstrating the paucity of effective treatments, particularly for late-stage disease. Globally, and in Aotearoa… read more here.
Keywords: new zealand; hepatitis; hepatocellular carcinoma; aotearoa new ... See more keywords
Human Epithelial Type-2 Cell Image Classification Using an Artificial Neural Network with Hybrid Descriptors
Sign Up to like & getrecommendations! Published in 2020 at "IETE Journal of Research"
DOI: 10.1080/03772063.2018.1474810
Abstract: ABSTRACT Antinuclear antibody (ANA) testing is best performed using the indirect immunofluorescence (IIF) method with human epithelial type-2 (HEp-2) cells as the substrate. IIF is a subjective procedure in which HEp-2 patterns are analyzed manually… read more here.
Keywords: epithelial type; image; hep; human epithelial ... See more keywords