Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin‐induced thrombocytopenia
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DOI: 10.1111/jth.14132
Abstract: Essentials The immunogenesis of Heparin‐induced thrombocytopenia (HIT) is not well understood. Immunization to platelet factor 4 (PF4)‐heparin occurs early in life, before any heparin exposure. PF4 and PF4‐heparin complexes induce the proliferation of CD14+ cells.… read more here.
Keywords: heparin; heparin complexes; induced thrombocytopenia; heparin induced ... See more keywords