Effects of heparin and derivatives on podocytes: An in vitro functional and morphological evaluation
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DOI: 10.1002/jcp.28191
Abstract: Unfractionated heparin (UFH) and low molecular heparin derivatives (LMWH) display numerous biological properties in addition to their anticoagulant effects. However, due to the physicochemical heterogeneity of these drugs, a better understanding concerning their effects on… read more here.
Keywords: podocytes vitro; effects heparin; heparin derivatives; derivatives podocytes ... See more keywords
Therapeutic use of heparin and derivatives beyond anticoagulation in patients with bronchial asthma or COPD
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2018.01.006
Abstract: Graphical abstract Figure. No caption available. HighlightsHeparin is a unique molecule in biology with multiple pharmacological properties.Heparin therapy has benefits in patients with COPD and asthma.Inhaled heparin is safe and without adverse events associated with… read more here.
Keywords: heparin; copd asthma; therapeutic use; use heparin ... See more keywords
Heparin and its derivatives in the treatment of arterial thrombosis: a review
Sign Up to like & getrecommendations! Published in 2018 at "Veterinarni Medicina"
DOI: 10.17221/3014-vetmed
Abstract: Arterial occlusion due to thrombosis caused by ruptured atherosclerotic plaques has been recognized as a major cause of morbidity and mortality in western populations. Along with chronic heart failure it significantly decreases patient life expectancy.… read more here.
Keywords: treatment; treatment arterial; molecular weight; derivatives treatment ... See more keywords
The Challenge of Modulating Heparan Sulfate Turnover by Multitarget Heparin Derivatives
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DOI: 10.3390/molecules25020390
Abstract: This review comes as a part of the special issue “Emerging frontiers in GAGs and mimetics”. Our interest is in the manipulation of heparan sulfate (HS) turnover by employing HS mimetics/heparin derivatives that exert pleiotropic… read more here.
Keywords: heparin derivatives; sulfate turnover; heparan sulfate;