Rheological and clot microstructure evaluation of heparin neutralization by UHRA and protamine.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the mechanical behavior of biomedical materials"
DOI: 10.1016/j.jmbbm.2021.104851
Abstract: The current study reports the use of small amplitude oscillatory rheometry to investigate the dynamics of blood clot formation upon heparin neutralization under three different oscillatory frequencies, two of which were mimicking physiological heart rates.… read more here.
Keywords: clot; heparin neutralization; blood clot; blood ... See more keywords
Engineered Protein Copolymers for Heparin Neutralization and Detection
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01464
Abstract: Heparin is a widely applied anticoagulant agent. However, in clinical practice, it is of vital importance to reverse its anticoagulant effect to restore the blood-clotting cascade and circumvent side effects. Inspired by protein cages that… read more here.
Keywords: protein copolymers; engineered protein; heparin neutralization; detection ... See more keywords
INTRAOPERATIVE VALIDITY OF POINT OF CARE DURING PARTIAL HEPARIN NEUTRALIZATION
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cardiothoracic and Vascular Anesthesia"
DOI: 10.1053/j.jvca.2021.08.057
Abstract: Introduction Since 2019, at our Universitary Hospital, an unusual rate of patients had hemostasis abnormalities in immediate postoperative period of cardiac surgery. There was no change in practices explaining these anomalies. In order to assess… read more here.
Keywords: specificity; heparin neutralization; heparin; sensitivity ... See more keywords