Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly.
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DOI: 10.1016/j.bpj.2020.04.012
Abstract: Association of platelet factor 4 (PF4) with heparin is a first step in formation of aggregates implicated in the development of heparin-induced thrombocytopenia (HIT), a potentially fatal immune disorder affecting 1-5% of patients receiving heparin.… read more here.
Keywords: heparin; short heparin; heparin oligomers; platelet factor ... See more keywords