The iPSC Awakens ANGPTL3 in Tangier Disease
Sign Up to like & getrecommendations! Published in 2017 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2017.04.004
Abstract: Patients with genetic mutation of ATP-binding Cassette Transporter A1 (ABCA1), commonly known as Tangier Disease (TD), can be characterized by elevated levels of plasma triglycerides (hypertriglyceridemia) and low plasma high-density lipoprotein (HDL) levels. With current… read more here.
Keywords: ipsc awakens; abca1; hepatic abca1; hdl ... See more keywords
Role of ATP-binding cassette transporter A1 in suppressing lipid accumulation by glucagon-like peptide-1 agonist in hepatocytes
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DOI: 10.1016/j.molmet.2019.12.015
Abstract: Objective Adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1) influences hepatic cholesterol transportation. Accumulation of hepatic cholesterol leads to fatty liver disease, which is improved by glucagon-like peptide 1 (GLP-1) in diabetes. Therefore, we analyzed the… read more here.
Keywords: accumulation; lipid accumulation; hepatic abca1; atp binding ... See more keywords