Mitophagy Controls the Activities of Tumor Suppressor p53 to Regulate Hepatic Cancer Stem Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.09.022
Abstract: Autophagy is required for benign hepatic tumors to progress into malignant hepatocellular carcinoma. However, the mechanism is unclear. Here, we report that mitophagy, the selective removal of mitochondria by autophagy, positively regulates hepatic cancer stem… read more here.
Keywords: suppressor p53; cancer stem; tumor suppressor; hepatic cancer ... See more keywords
A Multifunctional Lipid-based Nanodevice for the Highly-specific Co-delivery of Sorafenib and Midkine siRNA to Hepatic Cancer Cells.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00738
Abstract: Hepatocellular carcinoma (HCC), a common deadly malignancy, requires novel therapeutic strategies to improve the survival rate. Combining chemotherapy and gene therapy is a promising approach for increasing efficiency and reducing side effects. We report on… read more here.
Keywords: specific delivery; highly specific; delivery; hepatic cancer ... See more keywords
Co-regulatory Network of Oncosuppressor miRNAs and Transcription Factors for Pathology of Human Hepatic Cancer Stem Cells (HCSC)
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41978-5
Abstract: Hepatic cancer stem cells (HCSCs) are considered as main players for the hepatocellular carcinoma (HCC) initiation, metastasis, drug resistance and recurrence. There is a growing evidence supporting the down-regulated miRNAs in HCSCs as key suppressors… read more here.
Keywords: cancer stem; pathology; hepatic cancer; cancer ... See more keywords
In silico analysis of the association between long non‐coding RNA family with sequence similarity 99 member A (FAM99A) and hepatic cancer
Sign Up to like & getrecommendations! Published in 2023 at "IET Systems Biology"
DOI: 10.1049/syb2.12062
Abstract: Abstract The link between family with sequence similarity 99 member A (FAM99A), a type of long non‐coding RNA, and tumourigenesis remains ambiguous. Therefore, in this study, the authors conducted an expression profile analysis of FAM99A… read more here.
Keywords: family sequence; hepatic cancer; expression; analysis ... See more keywords
Mitophagy and hepatic cancer stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Autophagy"
DOI: 10.1080/15548627.2018.1425058
Abstract: Jiyoung Lee, Kai Liu, Bangyan Stiles and Jing-hsiung James Ou Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Beijing You’an Hospital, Capital Medical University, Beijing,… read more here.
Keywords: cancer stem; hepatic cancer; microbiology; mitophagy hepatic ... See more keywords
Eco-friendly one-pot synthesis of some new pyrazolo[1,2-b]phthalazinediones with antiproliferative efficacy on human hepatic cancer cell lines
Sign Up to like & getrecommendations! Published in 2018 at "Green Chemistry Letters and Reviews"
DOI: 10.1080/17518253.2018.1474270
Abstract: ABSTRACT This work focuses the light on some remarkable achievements in clean and efficient green experimental synthesis, characterization and evaluation of the pharmaceutical and biochemical importance of new series of pyrazolo[1,2-b]phthalazinediones which synthesized through one-pot… read more here.
Keywords: one pot; cell lines; hepatic cancer; pyrazolo phthalazinediones ... See more keywords
Different effects of oxycodone and remifentanil in patients undergoing ultrasound-guided percutaneous radiofrequency ablation of hepatic cancer: a randomized trial
Sign Up to like & getrecommendations! Published in 2019 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s188728
Abstract: Background Percutaneous radiofrequency ablation (RFA) is a recently introduced alternative technique for the treatment of hepatic cancer. Anesthesia is required for RFA of hepatic cancer to achieve patient comfort and immobilization during this painful procedure.… read more here.
Keywords: hepatic cancer; percutaneous radiofrequency; guided percutaneous; ultrasound guided ... See more keywords
Effectiveness of capsaicin containing dried habanero pepper extract in the treatment of primary hepatic cancer in geriatric dogs.
Sign Up to like & getrecommendations! Published in 2018 at "Medycyna Weterynaryjna"
DOI: 10.21521/mw.5976
Abstract: Primary hepatic tumours constitute 0.6-1.3% of all tumours in dogs and 1.0-2.3% in cats. These neoplasms may originate in hepatic cells or bile ducts. Less frequently, they arise from neuroendocrine and mesenchymal tissue. Hepatocellular carcinoma… read more here.
Keywords: containing dried; primary hepatic; capsaicin containing; hepatic cancer ... See more keywords
Inhibition of induced-hepatic cancer in vivo through IQGAP1-shRNA gene therapy and modulation of TRAIL-induced apoptosis pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.998247
Abstract: Background Liver cancer is the deadliest malignancy among common tumors. It is the top cause of cancer-related deaths in Egypt, and it is characterized by increasing occurrence among the population. The objective of this study… read more here.
Keywords: control; hepatic cancer; group; iqgap1 shrna ... See more keywords
lncRNA LINC00152 knockdown suppressed hepatic cancer biological activity
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Medical Science"
DOI: 10.5114/aoms.2020.98425
Abstract: Hepatic cancer is one of the most lethal cancers and has a poor prognosis. The purpose of this study was to evaluate whether lncRNA LINC 00152 had effects on the development of hepatic cancer and… read more here.
Keywords: linc00152 knockdown; apoptosis; hepatic cancer; cancer ... See more keywords